ABI2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2ED0, 3P8C, 4N78 |
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Identifiers |
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Aliases | ABI2, ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBP1, argBPIA, argBPIB, abl-interactor 2, abl interactor 2, AIP1 |
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External IDs | OMIM: 606442; MGI: 106913; HomoloGene: 4209; GeneCards: ABI2; OMA:ABI2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 2 (human)[1] |
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| Band | 2q33.2 | Start | 203,328,239 bp[1] |
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End | 203,447,728 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 C2 | Start | 60,448,778 bp[2] |
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End | 60,520,317 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Brodmann area 23
- entorhinal cortex
- middle temporal gyrus
- postcentral gyrus
- external globus pallidus
- internal globus pallidus
- superior frontal gyrus
- superior vestibular nucleus
- ventral tegmental area
- lateral nuclear group of thalamus
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| Top expressed in | - lateral septal nucleus
- olfactory tubercle
- anterior amygdaloid area
- primary motor cortex
- ventromedial nucleus
- piriform cortex
- Region I of hippocampus proper
- cingulate gyrus
- subiculum
- nucleus accumbens
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- SH3 domain binding
- kinase binding
- protein binding
- cytoskeletal anchor activity
- proline-rich region binding
- ubiquitin protein ligase binding
- protein-containing complex binding
- protein tyrosine kinase activator activity
| Cellular component | - cytoplasm
- cytosol
- cell projection
- SCAR complex
- cytoskeleton
- lamellipodium
- filopodium
- filopodium tip
- dendrite
- nucleus
- adherens junction
- cell junction
- dendritic spine
| Biological process | - positive regulation of Arp2/3 complex-mediated actin nucleation
- cytoskeleton organization
- peptidyl-tyrosine phosphorylation
- Rac protein signal transduction
- viral process
- cell migration
- actin polymerization or depolymerization
- learning or memory
- dendrite development
- camera-type eye development
- nervous system development
- regulation of dendritic spine morphogenesis
- lens fiber cell morphogenesis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001282925 NM_001282926 NM_001282927 NM_001282932 NM_005759 |
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NM_001198570 NM_001198571 NM_198127 |
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RefSeq (protein) | NP_001269854 NP_001269855 NP_001269856 NP_001269861 NP_005750
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NP_001362591 NP_001362592 NP_001362593 NP_001362594 NP_001362595 NP_001362596 NP_001362597 NP_001362598 NP_001362599 NP_001362600 NP_001362601 NP_001362602 NP_001362603 NP_001362604 NP_001362605 NP_001362606 NP_001362607 NP_001362608 NP_001362609 NP_001362610 NP_001362611 NP_001362612 NP_001362613 NP_001362614 NP_001362615 NP_001362616 NP_001362617 NP_001362618 NP_001362619 NP_001362620 NP_001362621 NP_001362622 NP_001362624 NP_001362625 NP_001362627 NP_001362628 NP_001362631 NP_001362633 NP_001362635 NP_001362636 NP_001362637 NP_001362638 NP_001362639 NP_001362640 NP_001362641 NP_001362643 NP_001362646 NP_001362648 NP_001362650 NP_001362651 NP_001362652 NP_001362653 NP_001362654 NP_001362655 NP_001362656 NP_001362657 NP_001362658 NP_001362659 NP_001362660 NP_001362661 NP_001362662 NP_001362663 NP_001362664 NP_001362665 NP_001362666 NP_001362667 NP_001362668 NP_001362669 NP_001362670 NP_001362671 NP_001362672 NP_001362673 NP_001362674 NP_001362675 NP_001362676 NP_001362677 NP_001362678 NP_001362679 NP_001362680 NP_001362681 NP_001362682 NP_001362683 NP_001362684 |
| NP_001185499 NP_001185500 NP_937760 NP_001391634 NP_001391635
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NP_001391636 NP_001391637 NP_001391638 NP_001391639 NP_001391640 NP_001391641 NP_001391642 NP_001391643 NP_001391644 NP_001391645 NP_001391646 NP_001391647 NP_001391648 NP_001391649 NP_001391650 |
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Location (UCSC) | Chr 2: 203.33 – 203.45 Mb | Chr 1: 60.45 – 60.52 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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