Protein-coding gene in humans
| CPNE7 |
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| Identifiers |
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| Aliases | CPNE7, copine 7 |
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| External IDs | OMIM: 605689; MGI: 2142747; HomoloGene: 65128; GeneCards: CPNE7; OMA:CPNE7 - orthologs |
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| Gene location (Human) |
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 | | Chr. | Chromosome 16 (human)[1] |
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| | Band | 16q24.3 | Start | 89,575,758 bp[1] |
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| End | 89,597,246 bp[1] |
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|
| Gene location (Mouse) |
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 | | Chr. | Chromosome 8 (mouse)[2] |
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| | Band | 8|8 E1 | Start | 123,844,113 bp[2] |
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| End | 123,861,921 bp[2] |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - lateral nuclear group of thalamus
- stromal cell of endometrium
- parotid gland
- pituitary gland
- cingulate gyrus
- anterior cingulate cortex
- anterior pituitary
- right frontal lobe
- hypothalamus
- dorsal motor nucleus of vagus nerve
|
| | Top expressed in | - subiculum
- dentate gyrus of hippocampal formation granule cell
- primary visual cortex
- hippocampus proper
- medial dorsal nucleus
- superior frontal gyrus
- lateral septal nucleus
- anterior amygdaloid area
- nucleus of stria terminalis
- subdivision of hippocampus
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| | More reference expression data |
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| BioGPS | |
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| Gene ontology |
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| Molecular function | - protein binding
- transporter activity
- calcium-dependent phospholipid binding
| | Cellular component | - cytoplasm
- plasma membrane
- extracellular exosome
- membrane
- nucleus
| | Biological process | - cellular response to calcium ion
- glycerophospholipid biosynthetic process
- lipid metabolism
- transport
| | Sources:Amigo / QuickGO |
|
| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 16: 89.58 – 89.6 Mb | Chr 8: 123.84 – 123.86 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
|
Copine 7 is a protein that in humans is encoded by the CPNE7 gene. [5]
Function
This gene encodes a member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains and one von Willebrand factor A domain. The encoded protein may be involved in membrane trafficking. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000178773 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034796 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Copine 7". Retrieved 2017-01-19.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
