CYP3A7 |
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Identifiers |
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Aliases | CYP3A7, CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, cytochrome P450 family 3 subfamily A member 7, P450HLp2 |
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External IDs | OMIM: 605340; MGI: 88610; HomoloGene: 133564; GeneCards: CYP3A7; OMA:CYP3A7 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 7 (human)[1] |
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| Band | 7q22.1 | Start | 99,705,036 bp[1] |
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End | 99,735,196 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5 G2|5 76.89 cM | Start | 137,891,194 bp[2] |
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End | 137,919,881 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - buccal mucosa cell
- liver
- right lobe of liver
- testicle
- gonad
- kidney tubule
- gallbladder
- jejunal mucosa
- duodenum
- metanephric glomerulus
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| Top expressed in | - duodenum
- jejunum
- ileum
- left lobe of liver
- intestinal villus
- epithelium of small intestine
- epithelium of stomach
- left colon
- mucous cell of stomach
- gallbladder
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
- aromatase activity
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- iron ion binding
- oxidoreductase activity
- heme binding
- oxygen binding
- metal ion binding
- steroid hydroxylase activity
- estrogen 16-alpha-hydroxylase activity
- monooxygenase activity
- estrogen 2-hydroxylase activity
| Cellular component | - endoplasmic reticulum membrane
- organelle membrane
- intracellular membrane-bounded organelle
- membrane
- endoplasmic reticulum
| Biological process | - xenobiotic metabolic process
- lipid hydroxylation
- steroid metabolic process
- estrogen metabolic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 7: 99.71 – 99.74 Mb | Chr 5: 137.89 – 137.92 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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