Dexamethasone acefurate

Chemical compound
Dexamethasone acefurate
Clinical data
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • [(8S,9R,10S,11S,13S,14S,16R,17R)-17-(2-Acetyloxyacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
CAS Number
  • 83880-70-0
PubChem CID
  • 656777
UNII
  • W4N6E1T46B
CompTox Dashboard (EPA)
  • DTXSID3022900 Edit this at Wikidata
Chemical and physical data
FormulaC29H33FO8
Molar mass528.573 g·mol−1
3D model (JSmol)
  • Interactive image
  • C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)OC(=O)C5=CC=CO5)C)O)F)C
InChI
  • InChI=1S/C29H33FO8/c1-16-12-21-20-8-7-18-13-19(32)9-10-26(18,3)28(20,30)23(33)14-27(21,4)29(16,24(34)15-37-17(2)31)38-25(35)22-6-5-11-36-22/h5-6,9-11,13,16,20-21,23,33H,7-8,12,14-15H2,1-4H3/t16-,20+,21+,23+,26+,27+,28+,29+/m1/s1
  • Key:DDIWRLSEGOVQQD-BJRLRHTOSA-N

Dexamethasone acefurate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.[1]

References

  1. ^ Morton IK, Hall JM (1999). "Dexamethasone acefurate". Concise Dictionary of Pharmacological Agents : Properties and Synonyms. Dordrecht: Springer Netherlands. p. 95. ISBN 9789401144391.


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Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


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