ERG28

Protein-coding gene in the species Homo sapiens
ERG28
Identifiers
AliasesERG28, NET51, C14orf1, chromosome 14 open reading frame 1, ergosterol biosynthesis 28 homolog
External IDsOMIM: 604576; MGI: 1915571; HomoloGene: 38284; GeneCards: ERG28; OMA:ERG28 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for ERG28
Genomic location for ERG28
Band14q24.3Start75,649,791 bp[1]
End75,660,876 bp[1]
Gene location (Mouse)
Chromosome 12 (mouse)
Chr.Chromosome 12 (mouse)[2]
Chromosome 12 (mouse)
Genomic location for ERG28
Genomic location for ERG28
Band12|12 D2Start85,862,222 bp[2]
End85,871,324 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • oocyte

  • nipple

  • human penis

  • gingival epithelium

  • left testis

  • right testis

  • corpus epididymis

  • retinal pigment epithelium

  • secondary oocyte

  • right lobe of liver
Top expressed in
  • genital tubercle

  • zygote

  • tail of embryo

  • yolk sac

  • dentate gyrus of hippocampal formation granule cell

  • left lobe of liver

  • ventricular zone

  • secondary oocyte

  • lip

  • right kidney
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • protein-macromolecule adaptor activity
  • molecular function
Cellular component
  • integral component of membrane
  • transport vesicle
  • endoplasmic reticulum
  • membrane
  • endoplasmic reticulum membrane
Biological process
  • steroid metabolic process
  • sterol biosynthetic process
  • lipid metabolism
  • steroid biosynthetic process
  • ergosterol biosynthetic process
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

11161

58520

Ensembl

ENSG00000133935

ENSMUSG00000021252

UniProt

Q9UKR5

Q9ERY9

RefSeq (mRNA)

NM_007176

NM_021446
NM_001360451
NM_001360813

RefSeq (protein)

NP_009107

NP_067421
NP_001347380
NP_001347742

Location (UCSC)Chr 14: 75.65 – 75.66 MbChr 12: 85.86 – 85.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ergosterol biosynthetic protein 28 is a protein that in humans is encoded by the ERG28 gene.[5][6][7][8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000133935 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021252 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Veitia RA, Ottolenghi C, Bissery MC, Fellous A (Oct 1999). "A novel human gene, encoding a potential membrane protein conserved from yeast to man, is strongly expressed in testis and cancer cell lines". Cytogenetics and Cell Genetics. 85 (3–4): 217–20. doi:10.1159/000015296. PMID 10449901. S2CID 45886286.
  6. ^ Schirmer EC, Florens L, Guan T, Yates JR, Gerace L (Sep 2003). "Nuclear membrane proteins with potential disease links found by subtractive proteomics". Science. 301 (5638): 1380–2. Bibcode:2003Sci...301.1380S. doi:10.1126/science.1088176. PMID 12958361. S2CID 23832536.
  7. ^ Gachotte D, Eckstein J, Barbuch R, Hughes T, Roberts C, Bard M (Jan 2001). "A novel gene conserved from yeast to humans is involved in sterol biosynthesis". Journal of Lipid Research. 42 (1): 150–4. doi:10.1016/S0022-2275(20)32347-6. PMID 11160377.
  8. ^ "Entrez Gene: C14orf1 chromosome 14 open reading frame 1".

Further reading

  • Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Oct 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  • Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL (Aug 2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proceedings of the National Academy of Sciences of the United States of America. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.


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