Epimestrol
Chemical compound
- G03GB03 (WHO)
- (8R,9S,13S,14S,16R,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol
- 7004-98-0
- 244809
- 214111
- 7IVE3SDZ38
- D04021
- DTXSID90859807
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- Interactive image
- C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@H]([C@H]2O)O)CCC4=C3C=CC(=C4)OC
InChI
- InChI=1S/C19H26O3/c1-19-8-7-14-13-6-4-12(22-2)9-11(13)3-5-15(14)16(19)10-17(20)18(19)21/h4,6,9,14-18,20-21H,3,5,7-8,10H2,1-2H3/t14-,15-,16+,17-,18-,19+/m1/s1
- Key:UHQGCIIQUZBJAE-RRQVMCLOSA-N
Epimestrol (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name, BANTooltip British Approved Name) (brand names Alene, Stimovul; former developmental code name ORG-817), also known as 3-methoxy-17-epiestriol, is a synthetic, steroidal estrogen and an estrogen ether and prodrug of 17-epiestriol.[1][2][3] It has been used as a component of ovulation induction in combination with gonadotropin-releasing hormone.[4]
See also
References
- ^ G.W.A. Milne (1 November 2017). Ashgate Handbook of Endocrine Agents and Steroids. Taylor & Francis. pp. 25–. ISBN 978-1-351-74347-1.
- ^ NLM MESH entry for Epimestrol
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 391–. ISBN 978-3-88763-075-1.
- ^ Maia H, Barbosa I, Maia H, Nascimento AJ, Bonfim de Souza M (1980). "Induction of ovulation with epimestrol and luteinizing hormone-releasing hormone (LH-RH)". Int J Gynaecol Obstet. 17 (5): 431–3. doi:10.1002/j.1879-3479.1980.tb00179.x. PMID 6103833. S2CID 22761848.
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Estrogens and antiestrogens
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Estrogen receptor modulators
- Androgens and antiandrogens
- Progestogens and antiprogestogens
- List of estrogens
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