FCRL2

Protein-coding gene in the species Homo sapiens
FCRL2
Identifiers
AliasesFCRL2, CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C, Fc receptor like 2
External IDsOMIM: 606509; HomoloGene: 57121; GeneCards: FCRL2; OMA:FCRL2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for FCRL2
Genomic location for FCRL2
Band1q23.1Start157,745,733 bp[1]
End157,777,132 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • buccal mucosa cell

  • spleen

  • lymph node

  • epithelium of nasopharynx

  • granulocyte

  • appendix

  • tonsil

  • superficial temporal artery

  • mucosa of ileum

  • blood
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • plasma membrane
  • membrane
  • integral component of membrane
  • cell surface
Biological process
  • cell-cell signaling
  • positive regulation of signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79368

n/a

Ensembl

ENSG00000132704

n/a

UniProt

Q96LA5

n/a

RefSeq (mRNA)

NM_001159488
NM_030764
NM_138738
NM_138739

n/a

RefSeq (protein)

NP_001152960
NP_110391

n/a

Location (UCSC)Chr 1: 157.75 – 157.78 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Fc receptor-like protein 2 is a protein that in humans is encoded by the FCRL2 gene.[3][4]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132704 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Xu MJ, Zhao R, Zhao ZJ (Feb 2001). "Molecular cloning and characterization of SPAP1, an inhibitory receptor". Biochem Biophys Res Commun. 280 (3): 768–75. doi:10.1006/bbrc.2000.4213. PMID 11162587.
  4. ^ "Entrez Gene: FCRL2 Fc receptor-like 2".

Further reading

  • Davis RS, Wang YH, Kubagawa H, Cooper MD (2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9772–7. Bibcode:2001PNAS...98.9772D. doi:10.1073/pnas.171308498. PMC 55528. PMID 11493702.
  • Miller I, Hatzivassiliou G, Cattoretti G, et al. (2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood. 99 (8): 2662–9. doi:10.1182/blood.V99.8.2662. PMID 11929751.
  • Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1". Immunogenetics. 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID 12037601. S2CID 9452957.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL". Immunogenetics. 59 (4): 323–8. doi:10.1007/s00251-007-0195-9. PMID 17273841. S2CID 1971426.


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