FGD4 |
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Identifiers |
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Aliases | FGD4, CMT4H, FRABP, ZFYVE6, FYVE, RhoGEF and PH domain containing 4 |
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External IDs | OMIM: 611104; MGI: 2183747; HomoloGene: 26727; GeneCards: FGD4; OMA:FGD4 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 12 (human)[1] |
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| Band | 12p11.21 | Start | 32,399,558 bp[1] |
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End | 32,646,050 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 16 (mouse)[2] |
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| Band | 16|16 A2- A3 | Start | 16,234,781 bp[2] |
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End | 16,418,413 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - jejunal mucosa
- Achilles tendon
- mucosa of ileum
- retinal pigment epithelium
- pancreatic epithelial cell
- trabecular bone
- visceral pleura
- mucosa of paranasal sinus
- lower lobe of lung
- Skeletal muscle tissue of biceps brachii
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| Top expressed in | - epithelium of small intestine
- retinal pigment epithelium
- pineal gland
- interventricular septum
- granulocyte
- Epithelium of choroid plexus
- ciliary body
- iris
- epithelium of stomach
- Rostral migratory stream
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - metal ion binding
- small GTPase binding
- actin binding
- guanyl-nucleotide exchange factor activity
| Cellular component | - cytoplasm
- cytosol
- Golgi apparatus
- cell projection
- filopodium
- ruffle
- cytoskeleton
- lamellipodium
| Biological process | - regulation of GTPase activity
- filopodium assembly
- cytoskeleton organization
- regulation of cell shape
- positive regulation of apoptotic process
- regulation of Rho protein signal transduction
- regulation of small GTPase mediated signal transduction
- actin cytoskeleton organization
- G protein-coupled receptor signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001304480 NM_001304481 NM_001304483 NM_001304484 NM_139241
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NM_001330373 NM_001330374 NM_001370297 NM_001370298 NM_001384126 NM_001384127 NM_001384128 NM_001384130 NM_001384131 NM_001384132 NM_001385118 |
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NM_001301817 NM_001301818 NM_139232 NM_139233 NM_139234 |
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RefSeq (protein) | NP_001291409 NP_001291410 NP_001291412 NP_001291413 NP_001317302
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NP_001317303 NP_640334 NP_001357226 NP_001357227 NP_001371055 NP_001371056 NP_001371057 NP_001371059 NP_001371060 NP_001371061 NP_001291412.1 |
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NP_001288746 NP_001288747 NP_631978 |
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Location (UCSC) | Chr 12: 32.4 – 32.65 Mb | Chr 16: 16.23 – 16.42 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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