Flavone
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IUPAC name 2-phenylchromen-4-one | |
Identifiers | |
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3D model (JSmol) |
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Beilstein Reference | 157598 |
ChEBI |
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ChEMBL |
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ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.007.623 |
EC Number |
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Gmelin Reference | 1224858 |
IUPHAR/BPS |
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KEGG |
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PubChem CID |
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RTECS number |
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UNII |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C15H10O2 |
Molar mass | 222.243 g·mol−1 |
Appearance | white solid |
Melting point | 96–97 °C (205–207 °F; 369–370 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Flavone is an organic compound with the formula C6H4OC3H(Ph)O. A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products.[1] Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone.[2] Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone.
References
- ^ Gaspar, Alexandra; Matos, Maria João; Garrido, Jorge; Uriarte, Eugenio; Borges, Fernanda (2014). "Chromone: A Valid Scaffold in Medicinal Chemistry". Chemical Reviews. 114 (9): 4960–4992. doi:10.1021/cr400265z.
- ^ T. S. Wheeler (1952). "Flavone". Organic Syntheses. 32: 72. doi:10.15227/orgsyn.032.0072.
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Flavones and their conjugates
Monohydroxyflavone | |
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Dihydroxyflavones | |
Trihydroxyflavones | |
Tetrahydroxyflavones | |
Pentahydroxyflavones |
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O-methylated flavones |
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of apigenin | |
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of baicalein | |
of hypolaetin |
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of luteolin |
- Giraldiin A and B
- Nepitrin
- Oroxindin
- Scutellarin
Theograndin I and II