HAUS1

Protein-coding gene in the species Homo sapiens

HAUS1
Identifiers
AliasesHAUS1, CCDC5, HEI-C, HEIC, HsT1461, HAUS augmin like complex subunit 1
External IDsOMIM: 608775; MGI: 2385076; HomoloGene: 15516; GeneCards: HAUS1; OMA:HAUS1 - orthologs
Gene location (Mouse)
Chromosome 18 (mouse)
Chr.Chromosome 18 (mouse)[1]
Chromosome 18 (mouse)
Genomic location for HAUS1
Genomic location for HAUS1
Band18|18 E3Start77,757,567 bp[1]
End77,767,780 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • ganglionic eminence

  • monocyte

  • stromal cell of endometrium

  • rectum

  • Achilles tendon

  • smooth muscle tissue

  • bone marrow

  • gallbladder

  • lymph node

  • appendix
Top expressed in
  • spermatid

  • spermatocyte

  • yolk sac

  • testicle

  • epiblast

  • embryo

  • blastocyst

  • embryo

  • ventricular zone

  • bone marrow
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • molecular function
Cellular component
  • microtubule organizing center
  • centrosome
  • spindle
  • spindle pole
  • microtubule
  • HAUS complex
  • cytoskeleton
  • cytoplasm
  • cytosol
Biological process
  • spindle assembly
  • cell cycle
  • cell division
  • G2/M transition of mitotic cell cycle
  • ciliary basal body-plasma membrane docking
  • centrosome cycle
  • regulation of G2/M transition of mitotic cell cycle
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

115106

225745

Ensembl

n/a

ENSMUSG00000041840

UniProt

Q96CS2

Q8BHX1

RefSeq (mRNA)

NM_138443

NM_146089
NM_001357531
NM_001357532
NM_001357533

RefSeq (protein)

NP_612452

NP_666201
NP_001344460
NP_001344461
NP_001344462

Location (UCSC)n/aChr 18: 77.76 – 77.77 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

HAUS augmin-like complex subunit 1 is a protein that in humans is encoded by the HAUS1 gene.[4][5][6]


References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041840 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  5. ^ Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, et al. (May 2009). "HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity". Curr Biol. 19 (10): 816–26. Bibcode:2009CBio...19..816L. doi:10.1016/j.cub.2009.04.033. PMID 19427217. S2CID 2893122.
  6. ^ "Entrez Gene: CCDC5 coiled-coil domain containing 5 (spindle associated)".

Further reading

  • Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Einarson MB, Cukierman E, Compton DA, Golemis EA (2004). "Human Enhancer of Invasion-Cluster, a Coiled-Coil Protein Required for Passage through Mitosis". Mol. Cell. Biol. 24 (9): 3957–71. doi:10.1128/MCB.24.9.3957-3971.2004. PMC 387757. PMID 15082789.
  • Ramachandran N, Hainsworth E, Bhullar B, Eisenstein S, Rosen B, Lau AY, et al. (2004). "Self-assembling protein microarrays". Science. 305 (5680): 86–90. Bibcode:2004Sci...305...86R. doi:10.1126/science.1097639. PMID 15232106. S2CID 20936301.
  • Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.


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