Heparan sulfate 6-O-sulfotransferase

Heparan sulfate 6-sulfotransferase

Identifiers

Symbol

HS6ST

Pfam

PF03567

InterPro

IPR005331

Membranome

497

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Heparan sulfate 6-sulfotransferases catalyses the transfer of sulfate from adenosine 3'-phosphate, 5'-phosphosulfate to the 6th position of the N-sulfoglucosamine residue in heparan sulfate.^[1]

Human proteins containing this domain

HS6ST1
HS6ST2
HS6ST3

References

^ Matsuda Y, Kuroiwa A, Tanaka M, Habuchi H, Miyake G, Nogami K, Kusche-gullberg M, Habuchi O, Kimata K (2003). "Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties". Biochem. J. 371 (Pt 1): 131–142. doi:10.1042/BJ20021259. PMC 1223259. PMID 12492399.

This article incorporates text from the public domain Pfam and InterPro: IPR010635

Transferases: sulfur-containing group (EC 2.8)

2.8.1: Sulfurtransferases

Thiosulfate sulfurtransferase
- Rhodanese
3-mercaptopyruvate sulfurtransferase
thiosulfate—thiol sulfurtransferase
tRNA sulfurtransferase
thiosulfate—dithiol sulfurtransferase
biotin synthase
cysteine desulfurase

2.8.2: Sulfotransferases

2.8.3: CoA-transferases

Propionate CoA-transferase

2.8.4: Alkylthio

Coenzyme-B sulfoethylthiotransferase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)