K. B. Sainis
- Savitribai Phule Pune University
- Bhabha Atomic Research Centre
- Tufts University School of Medicine
- University College London
- Immunology
Krishna Balaji Sainis (born 2 October 1949) is an Indian immunologist. He is a former senior professor of Life Sciences at Homi Bhabha National Institute and an elected fellow of the National Academy of Sciences, India. Since 1999, he has served as the Indian representative on the United Nations Scientific Committee on the Effects of Atomic Radiation. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology for his contributions to medical sciences in 1994.
Biography
![](http://upload.wikimedia.org/wikipedia/commons/thumb/0/06/University_of_Pune%2C_Pune.jpg/220px-University_of_Pune%2C_Pune.jpg)
Born on 2 October 1949, K. B. Sainis earned a master's degree in biochemistry (MSc) from Savitribai Phule Pune University and did a one-year course in biology and radiobiology at Bhabha Atomic Research Centre (BARC).[1] Upon completion of the course in 1972, he joined BARC as a Scientific Officer while continuing his doctoral studies at Pune University and secured a PhD in biophysics in 1980. Taking a sabbatical, he did his post-doctoral studies at the New England Medical Centre of Tufts University School of Medicine and, with the assistance of an IAEA fellowship, he completed his studies at University College London at its ICRF Tumor Immunology Unit.[2]
Returning to BARC, he served in many positions, heading the Immunology Section and the Cell Biology Division and serving as the associate director of the Bioscience Group. He became director of the Bio-Medical Group in 2006, with the responsibility of six divisions.[3] During his service at BARC, he has also been working as a faculty at the department of Life Sciences of the Homi Bhabha National Institute where he is a senior professor.[2]
Sainis is married to Jayashree Krishna Sainis, a biochemist, and the family lives in Navi Mumbai.[4]
Research
Sainis' studies in immunobiology have covered how T Cells and their receptors influence immune response to DNA in mycobacterial antigens and lupus nephritis, an autoimmune disease.[5] He headed a group of scientists at BARC who were involved in research on immunomodulators based on plants.[6] His studies have been documented and cited in texts and articles.[note 1][7][8][9][10][11] He has also written chapters in books published by others.[12][13][14]
Affiliations and memberships
Sainis has been associated with two international agencies. He served as president of the Standing Advisory Group on Nuclear Applications (SAGNA) of the International Atomic Energy Agency (IAEA) in 2012, and since 1999 has served as the Indian representative on the United Nations Scientific Committee on the Effects of Atomic Radiation.[1][15][16]
Sainis is the president of the Mumbai Immunology Group at Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) of the Tata Memorial Centre[17] and a former vice president of the Maharashtra Academy of Sciences.[18] He is an honorary adviser to the Society for Free Radical Research India (SFRR-India);[19][20] a member of the Advisory Committee of the National Training Program on Radiation Processing of Food for Food and Quarantine Inspectors & Quality Control Personnel organized by Department of Atomic Energy in association with BARC in February 2013;[21] and a member of the Indian Immunology Society.[22]
He was previously associated with ongoing education programs such as the XVII Training Workshop on Radiation Emergency Preparedness for Medical Officers,[23] the Refresher Course 2013 of the Indian Women Scientists Association,[24] and the AKRUTI Technology Package for Rural Deployment of BARC.[25] He has delivered several invited speeches or keynote addresses[26][27] and is a reviewer for Hindawi journals.[28]
Awards and honors
The Council of Scientific and Industrial Research awarded Sainis the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards, in 1994.[29][30] The National Academy of Sciences, India elected him as a fellow in 2002.[31] He is also an elected fellow of the Maharashtra Academy of Sciences.[32]
Selected bibliography
Chapters
- K. B. Sainis, Sumariwalla, P. F., Goel, A., Chintalwar, G. J., Sipahimalani, A. T., and Banerji, A. (1997). S.N. Upadhyay (ed.). Immunomodulation - Immunomodulatory properties of stem extracts of Tinospora cordifolia: cell targets and active principles. Narosa Publishing House. p. 155.
{{cite book}}
: CS1 maint: multiple names: authors list (link) - Shakti N. Upadhyay (1999). Immunopharmacology: Strategies for Immunotherapy. CRC Press. pp. 10–. ISBN 978-0-8493-0951-9.
- Vibha Rani; Umesh Chand Singh Yadav (14 November 2014). Free Radicals in Human Health and Disease. Springer. pp. 349–. ISBN 978-81-322-2035-0.
Articles
- Raghu R, Sharma D, Ramakrishnan R, Khanam S, Chintalwar GJ, Sainis KB (2009). "Molecular events in the activation of B cells and macrophages by a non-microbial TLR4 agonist, G1-4A from Tinospora cordifolia". Immunol. Lett. 23 (1): 60–71. doi:10.1016/j.imlet.2009.02.005. PMID 19428553.
- Deepak Sharma, S. Santosh Kumar, Rahul Checker, Rashmi Raghu, Shazia Khanam, Sunil Krishnan, Krishna Balaji Sainis (2009). "Spatial distribution, kinetics, signaling and cytokine production during homeostasis driven proliferation of CD4+ T cells". Mol. Immunol. 46 (11–12): 2403–2412. doi:10.1016/j.molimm.2009.04.019. PMC 3090723. PMID 19447493.
{{cite journal}}
: CS1 maint: multiple names: authors list (link) - Checker R, Sandur SK, Sharma D, Patwardhan RS, Jayakumar S, Kohli V, Sethi G, Aggarwal BB, Sainis KB (2012). "Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT". PLOS ONE. 7 (2): e31318. Bibcode:2012PLoSO...731318C. doi:10.1371/journal.pone.0031318. PMC 3282718. PMID 22363615.
- Patwardhan RS, Checker R, Sharma D, Sandur SK, Sainis KB (2013). "Involvement of ERK-Nrf-2 signaling in ionizing radiation induced cell death in normal and tumor cells". PLOS ONE. 8 (6): e65929. Bibcode:2013PLoSO...865929P. doi:10.1371/journal.pone.0065929. PMC 3679038. PMID 23776571.
- Suryavanshi S, Sharma D, Checker R, Thoh M, Gota V, Sandur SK, Sainis KB (2015). "Amelioration of radiation-induced hematopoietic syndrome by an antioxidant chlorophyllin through increased stem cell activity and modulation of hematopoiesis". Free Radic Biol Med. 85: 56–70. doi:10.1016/j.freeradbiomed.2015.04.007. PMID 25872101.
See also
Notes
- ^ Please see Selected bibliography section
References
- ^ a b "Professor Dr. Krishna B. Sainis on UNSCEAR". UN Scientific Committee on the Effects of Atomic Radiation. 2017.
- ^ a b "Senior professor - Life Sciences". Homi Bhabha National Institute. 2017.
- ^ "Dr. Krishna Balaji Sainis on Vidwan". Vidwan Iflibnet. 2017.
- ^ "NASI fellows". National Academy of Sciences, India. 2017. Archived from the original on 16 March 2016.
- ^ "Handbook of Shanti Swarup Bhatnagar Prize Winners" (PDF). Council of Scientific and Industrial Research. 1999. p. 71. Archived from the original (PDF) on 4 March 2016. Retrieved 13 March 2017.
- ^ PHISPC; Burma and Chakravorty (1900). From Physiology and Chemistry to Biochemistry. Pearson Education India. pp. 468–. ISBN 978-81-317-5373-6.
- ^ "Sainis KB [Author]". US National Library of Medicine. 2017.
- ^ Atta-ur-Rahman (17 February 2017). Studies in Natural Products Chemistry. Elsevier Science. pp. 486–. ISBN 978-0-444-63937-0.
- ^ United Nations. Scientific Committee on the Effects of Atomic Radiation (2009). Effects of Ionizing Radiation: UNSCEAR 2006 Report to the General Assembly, with Scientific Annexes. United Nations Publications. pp. 193–. ISBN 978-92-1-142270-2.
- ^ Thomas Bechtold; Rita Mussak (6 April 2009). Handbook of Natural Colorants. John Wiley & Sons. pp. 253–. ISBN 978-0-470-74496-3.
- ^ Dr. Mohd Yusuf (27 February 2016). GREEN DYES AND PIGMENTS: CLASSES AND APPLICATIONS. Lulu.com. pp. 163–. ISBN 978-1-329-93291-3.
- ^ Shakti N. Upadhyay (1999). Immunopharmacology: Strategies for Immunotherapy. CRC Press. pp. 10–. ISBN 978-0-8493-0951-9.
- ^ Vibha Rani; Umesh Chand Singh Yadav (14 November 2014). Free Radicals in Human Health and Disease. Springer. pp. 349–. ISBN 978-81-322-2035-0.
- ^ K. B. Sainis, Sumariwalla, P. F., Goel, A., Chintalwar, G. J., Sipahimalani, A. T., and Banerji, A. (1997). S.N. Upadhyay (ed.). Immunomodulation - Immunomodulatory properties of stem extracts of Tinospora cordifolia: cell targets and active principles. Narosa Publishing House. p. 155.
{{cite book}}
: CS1 maint: multiple names: authors list (link) - ^ United Nations. Scientific Committee on the Effects of Atomic Radiation (2008). Report of the United Nations Scientific Committee on the Effects of Atomic Radiation: Fifty-sixth Session (10-18 July 2008). United Nations Publications. pp. 30–. GGKEY:B5URFLG7851.
- ^ United Nations. Scientific Committee on the Effects of Atomic Radiation (2000). Sources and Effects of Ionizing Radiation: Sources. United Nations Publications. pp. 16–. ISBN 978-92-1-142238-2.
- ^ "President - Mumbai Immunology Group". Mumbai Immunology Group - ACTREC. 2017.
- ^ "Special ASET Colloquium" (PDF). Tata Institute of Fundamental Research. 2017.
- ^ "Current Managing Committee (2016-2018)". SFFR India. 2017.
- ^ "Honorary Advisers". AIIMS. 2017.
- ^ "Advisory Committee National Training Program on Radiation Processing" (PDF). Global Centre for Nuclear Energy Partnership. 2017.
- ^ "IIS Member" (PDF). Indian Immunology Society. 2017.
- ^ "XVII Training Workshop on Radiation Emergency Preparedness for Meeical Officers" (PDF). BARC. 2017.
- ^ "Refresher Course 2013". Indian Women Scientists Association. 2017. Archived from the original on 13 June 2019. Retrieved 13 March 2017.
- ^ "AKRUTI Technology Package for Rural Deployment". BARC. 2017. Archived from the original on 2 November 2018. Retrieved 13 March 2017.
- ^ "The Director, Bio-Medical Group, BARC, Mumbai, Dr. K.B. Sainis addressing". Sarkari Mirror. 25 September 2013.
- ^ "RADIATION AND SOCIETY: Benefits and Apprehensions". Tata Institute of Fundamental Research. 2017.
- ^ "India: Reviewers Hindawi journals". Hindawi. 2017.
- ^ "Medical Sciences". Council of Scientific and Industrial Research. 2017.[dead link]
- ^ "View Bhatnagar Awardees". Shanti Swarup Bhatnagar Prize. 2016. Retrieved 12 November 2016.
- ^ "Zone wise list of Fellows & Honorary Fellows" (PDF). National Academy of Sciences, India. 2017.
- ^ "MAS fellows". Maharashtra Academy of Sciences. 2017.
External links
- Kalanithi Nesaretnam; Lester Packer (2001). Micronutrients and Health: Molecular Biological Mechanisms. The American Oil Chemists Society. pp. 56–. ISBN 978-1-893997-19-6.
- K G Ramawat (8 January 2004). Biotechnology of Medicinal Plants: Vitalizer and Therapeutic. Science Publishers. ISBN 978-1-57808-338-1.
Further reading
- "'No fear if it's nuclear'". News report. Mid-Day. 8 August 2013.
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