KIF14 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | KIF14, MKS12, kinesin family member 14, MCPH20 |
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External IDs | OMIM: 611279; MGI: 1098226; HomoloGene: 8916; GeneCards: KIF14; OMA:KIF14 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1q32.1 | Start | 200,551,497 bp[1] |
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End | 200,620,751 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1 E4|1 59.8 cM | Start | 136,394,081 bp[2] |
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End | 136,459,249 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - secondary oocyte
- trabecular bone
- gonad
- ventricular zone
- buccal mucosa cell
- testicle
- embryo
- bone marrow
- thymus
- ganglionic eminence
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| Top expressed in | - zygote
- tail of embryo
- genital tubercle
- secondary oocyte
- spermatocyte
- ventricular zone
- spermatid
- yolk sac
- blastocyst
- embryo
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - tubulin binding
- nucleotide binding
- protein kinase binding
- plus-end-directed microtubule motor activity
- PDZ domain binding
- microtubule motor activity
- microtubule binding
- ATP binding
- protein binding
- ATPase activity
| Cellular component | - spindle
- cytoplasm
- kinesin complex
- nucleus
- membrane
- midbody
- microtubule
- plasma membrane
- spindle midzone
- cytoskeleton
- cytosol
- Flemming body
| Biological process | - negative regulation of integrin activation
- cerebral cortex development
- negative regulation of apoptotic process
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
- regulation of neuron apoptotic process
- hippocampus development
- regulation of cell growth
- cell division
- substrate adhesion-dependent cell spreading
- regulation of G1/S transition of mitotic cell cycle
- cell proliferation in forebrain
- regulation of G2/M transition of mitotic cell cycle
- cerebellar granular layer structural organization
- olfactory bulb development
- microtubule depolymerization
- proteasome-mediated ubiquitin-dependent protein catabolic process
- cerebellar Purkinje cell layer structural organization
- regulation of myelination
- positive regulation of cell population proliferation
- regulation of Rap protein signal transduction
- cerebellar cortex development
- positive regulation of cytokinesis
- negative regulation of neuron apoptotic process
- establishment of protein localization
- regulation of cell migration
- mitotic metaphase plate congression
- regulation of cell maturation
- microtubule-based movement
- activation of protein kinase activity
- regulation of cell adhesion
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 200.55 – 200.62 Mb | Chr 1: 136.39 – 136.46 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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