Magnesium glycinate
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Names | |
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IUPAC name Magnesium diglycinate | |
Systematic IUPAC name Magnesium bis(aminoacetate) | |
Identifiers | |
CAS Number |
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ECHA InfoCard | 100.035.305 ![]() |
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CompTox Dashboard (EPA) |
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Properties | |
Chemical formula | C4H8MgN2O4 |
Molar mass | 172.423 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ![]() ![]() ![]() Infobox references |
Magnesium glycinate, also known as magnesium diglycinate or magnesium bisglycinate, is the magnesium salt of glycine (one magnesium and two glycine molecules), and is sold as a dietary supplement.[1][2] It contains 14.1% elemental magnesium by mass.
Magnesium glycinate is also often "buffered" with magnesium oxide but it is also available in its pure non-buffered magnesium glycinate[3] form.
Uses
Magnesium glycinate has been studied with applicability to patients with a bowel resection[1] or pregnancy-induced leg cramps.[2] Less scientific research exists on magnesium glycinate in therapeutic applications than other more common forms of magnesium salt such as magnesium chloride, oxide or citrate. Magnesium glycinate has been considered in the context of magnesium’s potential influence on systems associated with the development of depression.[3]
See also
- Magnesium (pharmaceutical preparation)
- Magnesium deficiency (medicine)
- Magnesium in biology
References
- ^ a b Schuette SA, Lashner BA, Janghorbani M (1994). "Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection". Journal of Parenteral and Enteral Nutrition. 18 (5): 430–5. doi:10.1177/0148607194018005430. PMID 7815675.
Magnesium diglycinate may be a good alternative to commonly used magnesium supplements in patients with intestinal resection.
- ^ a b Supakatisant C, Phupong V (2015). "Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial". Maternal & Child Nutrition. 11 (2): 139–45. doi:10.1111/j.1740-8709.2012.00440.x. PMC 6860204. PMID 22909270.
Forty-one women were assigned to magnesium bisglycinate chelate (300 mg per day) and 39 women to placebo. Details of leg cramps were recorded before beginning the treatment and the fourth week of study.
- ^ a b "Magnesium Bisglycinate". 88Herbs. 20 November 2014.
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III