NDST1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/2/26/Protein_NDST1_PDB_1nst.png/250px-Protein_NDST1_PDB_1nst.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | NDST1, HSST, NST1, MRT46, N-deacetylase/N-sulfotransferase 1, N-deacetylase and N-sulfotransferase 1 |
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External IDs | OMIM: 600853; MGI: 104719; HomoloGene: 20386; GeneCards: NDST1; OMA:NDST1 - orthologs |
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Gene location (Human) |
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![Chromosome 5 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/61/Ideogram_human_chromosome_5.svg/300px-Ideogram_human_chromosome_5.svg.png) | Chr. | Chromosome 5 (human)[1] |
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| Band | 5q33.1 | Start | 150,485,818 bp[1] |
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End | 150,558,211 bp[1] |
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Gene location (Mouse) |
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![Chromosome 18 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/5/5c/Ideogram_house_mouse_chromosome_18.svg/260px-Ideogram_house_mouse_chromosome_18.svg.png) | Chr. | Chromosome 18 (mouse)[2] |
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| Band | 18|18 E1 | Start | 60,817,566 bp[2] |
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End | 60,881,722 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - stromal cell of endometrium
- C1 segment
- olfactory bulb
- subthalamic nucleus
- inferior ganglion of vagus nerve
- right lobe of liver
- lateral nuclear group of thalamus
- mucosa of esophagus
- inferior olivary nucleus
- upper lobe of left lung
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| Top expressed in | - right lung lobe
- left lung
- left lung lobe
- lacrimal gland
- epithelium of stomach
- left lobe of liver
- human fetus
- salivary gland
- vas deferens
- digastric muscle
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/PBB_GE_NDST1_202608_s_at_fs.png/250px-PBB_GE_NDST1_202608_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- sulfotransferase activity
- deacetylase activity
- catalytic activity
- hydrolase activity
- N-acetylglucosamine deacetylase activity
- protein binding
- [heparan sulfate-glucosamine N-sulfotransferase activity]
- heparan sulfate N-acetylglucosaminyltransferase activity
- heparan sulfate sulfotransferase activity
| Cellular component | - integral component of membrane
- Golgi apparatus
- membrane
- Golgi membrane
| Biological process | - cardiac septum development
- heparin biosynthetic process
- embryonic neurocranium morphogenesis
- coronary vasculature development
- respiratory gaseous exchange by respiratory system
- fibroblast growth factor receptor signaling pathway
- aorta development
- heart development
- glycosaminoglycan biosynthetic process
- animal organ morphogenesis
- embryonic viscerocranium morphogenesis
- polysaccharide biosynthetic process
- forebrain development
- metabolism
- protein sulfation
- inflammatory response
- midbrain development
- glycosaminoglycan metabolic process
- heparan sulfate proteoglycan biosynthetic process
- heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
- positive regulation of MAPK cascade
- positive regulation of smoothened signaling pathway
- sulfur compound metabolic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | NM_008306 NM_001348100 NM_001348101 NM_001348102 NM_001348103
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NM_001348146 |
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RefSeq (protein) | | NP_032332 NP_001335029 NP_001335030 NP_001335031 NP_001335032
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NP_001335075 |
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Location (UCSC) | Chr 5: 150.49 – 150.56 Mb | Chr 18: 60.82 – 60.88 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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