P2RX3 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/2/25/5svq.jpg/250px-5svq.jpg) |
Identifiers |
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Aliases | P2RX3, P2X3, purinergic receptor P2X 3 |
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External IDs | OMIM: 600843; MGI: 1097160; HomoloGene: 1922; GeneCards: P2RX3; OMA:P2RX3 - orthologs |
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Gene location (Human) |
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![Chromosome 11 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png) | Chr. | Chromosome 11 (human)[1] |
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| Band | 11q12.1 | Start | 57,338,352 bp[1] |
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End | 57,372,396 bp[1] |
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Gene location (Mouse) |
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![Chromosome 2 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Ideogram_house_mouse_chromosome_2.svg/260px-Ideogram_house_mouse_chromosome_2.svg.png) | Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2|2 D | Start | 84,998,583 bp[2] |
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End | 85,037,462 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gonad
- testicle
- apex of heart
- left testis
- right testis
- left ventricle
- right lobe of liver
- left adrenal cortex
- right adrenal gland
- striated muscle tissue
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| Top expressed in | - lumbar spinal ganglion
- spermatid
- ganglion of vagus nerve
- trigeminal ganglion
- blastocyst
- seminiferous tubule
- Greater petrosal nerve
- spermatocyte
- neural tube
- tail of embryo
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - purinergic nucleotide receptor activity
- ion channel activity
- ATP binding
- extracellularly ATP-gated cation channel activity
- nucleotide binding
- ATP-gated ion channel activity
| Cellular component | - integral component of membrane
- rough endoplasmic reticulum
- Golgi apparatus
- membrane
- receptor complex
- dendritic spine
- integral component of nuclear inner membrane
- integral component of plasma membrane
- neuronal cell body
- terminal bouton
- axon
- membrane raft
- neuron projection
- plasma membrane
- Schaffer collateral - CA1 synapse
- hippocampal mossy fiber to CA3 synapse
- integral component of presynaptic membrane
| Biological process | - peristalsis
- response to ATP
- response to hypoxia
- positive regulation of calcium-mediated signaling
- positive regulation of calcium ion transport into cytosol
- urinary bladder smooth muscle contraction
- response to mechanical stimulus
- cation transport
- response to heat
- ion transport
- behavioral response to formalin induced pain
- response to organic substance
- cation transmembrane transport
- regulation of synaptic plasticity
- neuromuscular synaptic transmission
- positive regulation of sensory perception of pain
- behavioral response to pain
- response to cold
- protein homooligomerization
- response to carbohydrate
- sensory perception of taste
- signal transduction
- neuronal action potential
- response to temperature stimulus
- chemical synaptic transmission
- purinergic nucleotide receptor signaling pathway
- blood coagulation
- excitatory postsynaptic potential
- protein homotrimerization
- cellular response to ATP
- modulation of chemical synaptic transmission
- ion transmembrane transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 11: 57.34 – 57.37 Mb | Chr 2: 85 – 85.04 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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