PIK3R5 |
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Identifiers |
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Aliases | PIK3R5, F730038I15Rik, FOAP-2, P101-PI3K, p101, phosphoinositide-3-kinase regulatory subunit 5 |
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External IDs | OMIM: 611317; MGI: 2443588; HomoloGene: 8627; GeneCards: PIK3R5; OMA:PIK3R5 - orthologs |
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Gene location (Human) |
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![Chromosome 17 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 (human)[1] |
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| Band | 17p13.1 | Start | 8,878,911 bp[1] |
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End | 8,965,712 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B3 | Start | 68,322,947 bp[2] |
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End | 68,388,675 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - granulocyte
- blood
- monocyte
- spleen
- bone marrow cells
- upper lobe of left lung
- lymph node
- right lung
- appendix
- gallbladder
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| Top expressed in | - granulocyte
- thymus
- blood
- mesenteric lymph nodes
- stroma of bone marrow
- spleen
- outer nuclear layer
- otic vesicle
- subcutaneous adipose tissue
- lumbar subsegment of spinal cord
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/d/db/PBB_GE_PIK3R5_220566_at_fs.png/250px-PBB_GE_PIK3R5_220566_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - G-protein beta/gamma-subunit complex binding
- phosphatidylinositol-4,5-bisphosphate 3-kinase activity
- 1-phosphatidylinositol-3-kinase regulator activity
| Cellular component | - cytoplasm
- plasma membrane
- phosphatidylinositol 3-kinase complex, class IB
- membrane
- nucleus
- phosphatidylinositol 3-kinase complex
- microtubule organizing center
- cytosol
| Biological process | - platelet activation
- positive regulation of protein kinase B signaling
- regulation of phosphatidylinositol 3-kinase activity
- positive regulation of MAP kinase activity
- phosphatidylinositol 3-kinase signaling
- phosphatidylinositol phosphate biosynthetic process
- G protein-coupled receptor signaling pathway
- positive regulation of phosphatidylinositol 3-kinase signaling
- phosphatidylinositol biosynthetic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001142633 NM_001251851 NM_001251852 NM_001251853 NM_001251855
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NM_014308 NM_001388396 NM_001388397 NM_001388398 NM_001388399 NM_001388400 |
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RefSeq (protein) | NP_001136105 NP_001238780 NP_001238781 NP_001238782 NP_001238784
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NP_055123 |
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Location (UCSC) | Chr 17: 8.88 – 8.97 Mb | Chr 11: 68.32 – 68.39 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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