Protein-coding gene in the species Homo sapiens
PRSS55 |
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Identifiers |
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Aliases | PRSS55, CT153, T-SP1, TSP1, UNQ9391, protease, serine 55, serine protease 55 |
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External IDs | OMIM: 615144; MGI: 1918287; HomoloGene: 51233; GeneCards: PRSS55; OMA:PRSS55 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 8 (human)[1] |
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| Band | 8p23.1 | Start | 10,525,532 bp[1] |
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End | 10,554,166 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 14 (mouse)[2] |
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| Band | 14|14 D1 | Start | 64,075,438 bp[2] |
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End | 64,090,162 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gonad
- right testis
- left testis
- cerebellar cortex
- cerebellar hemisphere
- right hemisphere of cerebellum
- primary visual cortex
- amygdala
- Brodmann area 9
- C1 segment
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| Top expressed in | - seminiferous tubule
- spermatid
- spermatocyte
- gastrula
- lacrimal gland
- embryo
- quadriceps femoris muscle
- free upper limb
- intercostal muscle
- major salivary gland
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - peptidase activity
- serine-type peptidase activity
- hydrolase activity
- serine-type endopeptidase activity
| Cellular component | - cytoplasm
- integral component of membrane
- cytosol
- membrane
| Biological process | | Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | |
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ENSG00000184647 ENSG00000285141 |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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NP_001074532 NP_001366451 NP_001366452 |
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Location (UCSC) | Chr 8: 10.53 – 10.55 Mb | Chr 14: 64.08 – 64.09 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Serine protease 55 is a protein that in humans is encoded by the PRSS55 gene. [5]
Function
This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The encoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010].
References
- ^ a b c ENSG00000285141 GRCh38: Ensembl release 89: ENSG00000184647, ENSG00000285141 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034623 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Serine protease 55". Retrieved 2018-04-24.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.