PTPMT1 |
---|
|
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
List of PDB id codes |
---|
3RGO, 3RGQ |
|
|
Identifiers |
---|
Aliases | PTPMT1, DUSP23, MOSP, PLIP, PNAS-129, protein tyrosine phosphatase, mitochondrial 1, protein tyrosine phosphatase mitochondrial 1 |
---|
External IDs | OMIM: 609538; MGI: 1913711; HomoloGene: 11973; GeneCards: PTPMT1; OMA:PTPMT1 - orthologs |
---|
EC number | 3.1.3.48 |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 11 (human)[1] |
---|
| Band | 11p11.2 | Start | 47,565,430 bp[1] |
---|
End | 47,573,461 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 2 (mouse)[2] |
---|
| Band | 2|2 E1 | Start | 90,739,060 bp[2] |
---|
End | 90,748,389 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - left testis
- right testis
- putamen
- left adrenal cortex
- substantia nigra
- hypothalamus
- right adrenal gland
- caudate nucleus
- right adrenal cortex
- nucleus accumbens
|
| Top expressed in | - left ventricle
- interventricular septum
- quadriceps femoris muscle
- spermatid
- white adipose tissue
- testicle
- peripheral nervous system
- superior cervical ganglion
- muscle tissue
- muscle of thigh
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - phosphoprotein phosphatase activity
- phosphatase activity
- phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
- protein binding
- phosphatidylglycerophosphatase activity
- protein tyrosine phosphatase activity
- hydrolase activity
- protein tyrosine/serine/threonine phosphatase activity
| Cellular component | - membrane
- mitochondrion
- mitochondrial inner membrane
- nucleus
| Biological process | - lipid metabolism
- protein dephosphorylation
- phospholipid biosynthetic process
- cardiolipin biosynthetic process
- peptidyl-tyrosine dephosphorylation
- dephosphorylation
- phosphatidylglycerol biosynthetic process
- regulation of intrinsic apoptotic signaling pathway
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | |
---|
ENSG00000110536 ENSG00000285206 |
| |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protein) | | |
---|
Location (UCSC) | Chr 11: 47.57 – 47.57 Mb | Chr 2: 90.74 – 90.75 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|