Peptidase inhibitor 16

Protein-coding gene in the species Homo sapiens
PI16
Identifiers
AliasesPI16, CRISP9, MSMBBP, PSPBP, CD364, peptidase inhibitor 16
External IDsMGI: 1921366; HomoloGene: 134317; GeneCards: PI16; OMA:PI16 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for PI16
Genomic location for PI16
Band6p21.2Start36,948,263 bp[1]
End36,964,837 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for PI16
Genomic location for PI16
Band17|17 A3.3Start29,536,654 bp[2]
End29,549,567 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of arm

  • apex of heart

  • gastric mucosa

  • right auricle

  • vena cava

  • pancreatic ductal cell

  • right coronary artery

  • canal of the cervix

  • trachea

  • C1 segment
Top expressed in
  • granulocyte

  • lip

  • extraocular muscle

  • ascending aorta

  • aortic valve

  • ankle

  • esophagus

  • sciatic nerve

  • conjunctival fornix

  • tunica adventitia of aorta
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • peptidase inhibitor activity
Cellular component
  • extracellular region
  • extracellular space
Biological process
  • negative regulation of peptidase activity
  • negative regulation of cell growth involved in cardiac muscle cell development
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

221476

74116

Ensembl

ENSG00000164530

ENSMUSG00000024011

UniProt

Q6UXB8

Q9ET66

RefSeq (mRNA)

NM_001199159
NM_153370

NM_023734

RefSeq (protein)

NP_001186088
NP_699201

NP_076223

Location (UCSC)Chr 6: 36.95 – 36.96 MbChr 17: 29.54 – 29.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Peptidase inhibitor 16 is a protein that in humans is encoded by the PI16 gene. [5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164530 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024011 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Peptidase inhibitor 16". Retrieved 2017-10-07.

Further reading

  • Reeves JR, Xuan JW, Arfanis K, Morin C, Garde SV, Ruiz MT, Wisniewski J, Panchal C, Tanner JE (2005). "Identification, purification and characterization of a novel human blood protein with binding affinity for prostate secretory protein of 94 amino acids". Biochem. J. 385 (Pt 1): 105–14. doi:10.1042/BJ20040290. PMC 1134678. PMID 15344909.
  • Reeves JR, Dulude H, Panchal C, Daigneault L, Ramnani DM (2006). "Prognostic value of prostate secretory protein of 94 amino acids and its binding protein after radical prostatectomy". Clin. Cancer Res. 12 (20 Pt 1): 6018–22. doi:10.1158/1078-0432.CCR-06-0625. PMID 17062675.


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