Protein-coding gene in the species Homo sapiens
RPL36AL |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4UG0, 4V6X, 5AJ0 |
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Identifiers |
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Aliases | RPL36AL, RPL36A, ribosomal protein L36a like, RPL36A_18_1363, RPL36AP42 |
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External IDs | OMIM: 180469; MGI: 1913733; HomoloGene: 133572; GeneCards: RPL36AL; OMA:RPL36AL - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 14 (human)[1] |
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| Band | 14q21.3 | Start | 49,618,530 bp[1] |
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End | 49,620,626 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 12 (mouse)[2] |
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| Band | 12|12 C2 | Start | 69,229,505 bp[2] |
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End | 69,230,857 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - germinal epithelium
- epithelium of nasopharynx
- tendon of biceps brachii
- amniotic fluid
- seminal vesicula
- body of pancreas
- trabecular bone
- left ovary
- islet of Langerhans
- caput epididymis
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| Top expressed in | - yolk sac
- islet of Langerhans
- embryo
- lens
- primary oocyte
- stomach
- embryo
- epiblast
- thymus
- ileum
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - structural constituent of ribosome
- protein binding
| Cellular component | - cytoplasm
- ribosome
- intracellular anatomical structure
- nucleus
- cytosol
- plasma membrane
- cytosolic large ribosomal subunit
- endoplasmic reticulum
| Biological process | | Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 14: 49.62 – 49.62 Mb | Chr 12: 69.23 – 69.23 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Ribosomal protein L36a like is a protein that in humans is encoded by the RPL36AL gene. [5]
Function
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. This gene and the human gene officially named ribosomal protein L36a (RPL36A) encode nearly identical proteins; however, they are distinct genes. Although the name of this gene has been referred to as ribosomal protein L36a (RPL36A), its official name is ribosomal protein L36a-like (RPL36AL). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].[5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000165502 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049751 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: Ribosomal protein L36a like". Retrieved 2020-04-15. This article incorporates text from this source, which is in the public domain.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.