SLC8B1 |
---|
|
Identifiers |
---|
Aliases | SLC8B1, NCKX6, NCLX, SLC24A6, solute carrier family 8 member B1 |
---|
External IDs | OMIM: 609841; MGI: 2180781; HomoloGene: 41602; GeneCards: SLC8B1; OMA:SLC8B1 - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 12 (human)[1] |
---|
| Band | 12q24.13 | Start | 113,298,759 bp[1] |
---|
End | 113,359,493 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 5 (mouse)[2] |
---|
| Band | 5|5 F | Start | 120,649,233 bp[2] |
---|
End | 120,672,089 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - left adrenal cortex
- right adrenal gland
- right adrenal cortex
- left ovary
- right ovary
- spleen
- mucosa of transverse colon
- sural nerve
- granulocyte
- epithelium of colon
|
| Top expressed in | - granulocyte
- stroma of bone marrow
- decidua
- left lobe of liver
- lip
- tibiofemoral joint
- yolk sac
- left colon
- gastrula
- mesenteric lymph nodes
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - protein homodimerization activity
- identical protein binding
- antiporter activity
- calcium:cation antiporter activity
- calcium:sodium antiporter activity
- calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential
| Cellular component | - integral component of membrane
- membrane
- plasma membrane
- mitochondrial crista
- mitochondrion
- integral component of mitochondrial membrane
- sarcolemma
- mitochondrial inner membrane
| Biological process | - sodium ion transmembrane transport
- regulation of cytosolic calcium ion concentration
- glucose homeostasis
- response to stimulus
- regulation of insulin secretion
- sodium ion transport
- ion transport
- calcium ion transmembrane transport
- regulation of cardiac muscle cell membrane potential
- calcium ion transport
- transmembrane transport
- mitochondrial calcium ion transmembrane transport
- mitochondrial calcium ion homeostasis
- calcium export from the mitochondrion
- regulation of lymphocyte chemotaxis
- regulation of store-operated calcium entry
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | |
---|
NM_024959 NM_001330466 NM_001358345 |
| |
---|
NM_001177594 NM_001177595 NM_133221 |
|
---|
RefSeq (protein) | |
---|
NP_001317395 NP_079235 NP_001345274 |
| |
---|
NP_001171065 NP_001171066 NP_573484 |
|
---|
Location (UCSC) | Chr 12: 113.3 – 113.36 Mb | Chr 5: 120.65 – 120.67 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|