SNF8 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Protein_VPS25_PDB_2ZME.png/250px-Protein_VPS25_PDB_2ZME.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2ZME, 3CUQ |
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Identifiers |
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Aliases | SNF8, Dot3, EAP30, VPS22, ESCRT-II complex subunit, SNF8 subunit of ESCRT-II |
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External IDs | OMIM: 610904; MGI: 1343161; HomoloGene: 5239; GeneCards: SNF8; OMA:SNF8 - orthologs |
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Gene location (Human) |
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![Chromosome 17 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 (human)[1] |
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| Band | 17q21.32 | Start | 48,929,316 bp[1] |
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End | 48,944,842 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11 D|11 59.24 cM | Start | 95,925,711 bp[2] |
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End | 95,938,256 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - apex of heart
- mucosa of transverse colon
- gastric mucosa
- stromal cell of endometrium
- left coronary artery
- ganglionic eminence
- right auricle
- right adrenal gland
- popliteal artery
- tibial arteries
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| Top expressed in | - embryo
- yolk sac
- morula
- dentate gyrus of hippocampal formation granule cell
- epiblast
- blastocyst
- right kidney
- superior frontal gyrus
- facial motor nucleus
- duodenum
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/c/ce/PBB_GE_SNF8_218391_at_fs.png/250px-PBB_GE_SNF8_218391_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein homodimerization activity
- protein N-terminus binding
- transcription factor binding
- protein C-terminus binding
- channel regulator activity
- protein binding
| Cellular component | - cytoplasm
- recycling endosome
- cytosol
- endosome
- membrane
- late endosome membrane
- transcription regulator complex
- plasma membrane
- nucleoplasm
- perinuclear region of cytoplasm
- endosome membrane
- extracellular exosome
- nucleus
- ESCRT II complex
| Biological process | - regulation of transcription, DNA-templated
- positive regulation of protein catabolic process
- multivesicular body sorting pathway
- regulation of transcription by RNA polymerase II
- multivesicular body assembly
- regulation of multivesicular body size involved in endosome transport
- transcription, DNA-templated
- endosomal transport
- regulation of protein complex stability
- positive regulation of gene expression
- early endosome to late endosome transport
- endocytic recycling
- regulation of protein catabolic process
- protein transport
- regulation of MAP kinase activity
- positive regulation of exosomal secretion
- protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
- macroautophagy
- regulation of molecular function
- transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_007241 NM_001317192 NM_001317193 NM_001317194 |
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RefSeq (protein) | |
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NP_001304121 NP_001304122 NP_001304123 NP_009172 |
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Location (UCSC) | Chr 17: 48.93 – 48.94 Mb | Chr 11: 95.93 – 95.94 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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