SNX3 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2YPS, 2MXC |
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Identifiers |
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Aliases | SNX3, Grd19, MCOPS8, SDP3, sorting nexin 3 |
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External IDs | OMIM: 605930; MGI: 1860188; HomoloGene: 36144; GeneCards: SNX3; OMA:SNX3 - orthologs |
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Gene location (Human) |
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![Chromosome 6 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Ideogram_human_chromosome_6.svg/300px-Ideogram_human_chromosome_6.svg.png) | Chr. | Chromosome 6 (human)[1] |
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| Band | 6q21 | Start | 108,211,222 bp[1] |
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End | 108,261,246 bp[1] |
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Gene location (Mouse) |
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![Chromosome 10 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_house_mouse_chromosome_10.svg/260px-Ideogram_house_mouse_chromosome_10.svg.png) | Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10 B2|10 22.89 cM | Start | 42,378,026 bp[2] |
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End | 42,411,377 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - trabecular bone
- middle temporal gyrus
- visceral pleura
- parietal pleura
- endothelial cell
- right ventricle
- germinal epithelium
- parotid gland
- Epithelium of choroid plexus
- Brodmann area 23
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| Top expressed in | - lactiferous gland
- CA3 field
- pyloric antrum
- yolk sac
- fetal liver hematopoietic progenitor cell
- calvaria
- plantaris muscle
- facial motor nucleus
- perirhinal cortex
- entorhinal cortex
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/6/67/PBB_GE_SNX3_213545_x_at_fs.png/250px-PBB_GE_SNX3_213545_x_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/c/c8/PBB_GE_SNX3_210648_x_at_fs.png/250px-PBB_GE_SNX3_210648_x_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - phosphatidylinositol-3-phosphate binding
- phosphatidylinositol-3,5-bisphosphate binding
- phosphatidylinositol-4-phosphate binding
- phosphatidylinositol-5-phosphate binding
- protein binding
- phosphatidylinositol binding
- protein phosphatase binding
- lipid binding
- phosphatidylinositol phosphate binding
| Cellular component | - cytoplasm
- cytosol
- endosome
- early endosome membrane
- early phagosome
- retromer complex
- early endosome
- phagocytic vesicle
- extracellular exosome
- cytoplasmic vesicle
- clathrin-coated vesicle
- extrinsic component of membrane
- endosome membrane
| Biological process | - protein to membrane docking
- negative regulation of viral entry into host cell
- negative regulation of phagocytosis
- response to bacterium
- negative regulation of protein catabolic process
- negative regulation of early endosome to late endosome transport
- membrane invagination
- regulation of Wnt signaling pathway
- intralumenal vesicle formation
- negative regulation of protein transport
- positive regulation of neuron projection development
- protein transport
- Wnt signaling pathway
- protein deubiquitination
- transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_152828 NM_001300928 NM_001300929 NM_003795 NM_152827 |
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RefSeq (protein) | |
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NP_001287857 NP_001287858 NP_003786 NP_690040 |
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Location (UCSC) | Chr 6: 108.21 – 108.26 Mb | Chr 10: 42.38 – 42.41 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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