Troxacitabine

Chemical compound
Troxacitabine
Identifiers
  • 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2(1H)-one
CAS Number
  • 145918-75-8 ☒N
PubChem CID
  • 151173
ChemSpider
  • 399955 checkY
UNII
  • 60KQZ0388Y
ChEMBL
  • ChEMBL359164 checkY
CompTox Dashboard (EPA)
  • DTXSID2048791 Edit this at Wikidata
Chemical and physical data
FormulaC8H11N3O4
Molar mass213.193 g·mol−1
3D model (JSmol)
  • Interactive image
  • O=C1/N=C(/N)\C=C/N1[C@H]2O[C@H](OC2)CO
InChI
  • InChI=1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1 checkY
  • Key:RXRGZNYSEHTMHC-BQBZGAKWSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Troxacitabine (brand name Troxatyl) is a nucleoside analogue with anticancer activity. Its use is being studied in patients with refractory lymphoproliferative diseases.[1]

References

  1. ^ Vose JM, Panwalkar A, Belanger R, Coiffier B, Baccarani M, Gregory SA, et al. (January 2007). "A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma". Leukemia & Lymphoma. 48 (1): 39–45. doi:10.1080/10428190600909578. PMID 17325846. S2CID 36220728.
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