USP13 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2L80, 2LBC |
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Identifiers |
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Aliases | USP13, ISOT3, IsoT-3, ubiquitin specific peptidase 13 (isopeptidase T-3), ubiquitin specific peptidase 13 |
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External IDs | OMIM: 603591; MGI: 1919857; HomoloGene: 68372; GeneCards: USP13; OMA:USP13 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3q26.33 | Start | 179,653,032 bp[1] |
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End | 179,804,366 bp[1] |
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Gene location (Mouse) |
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![Chromosome 3 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Ideogram_house_mouse_chromosome_3.svg/260px-Ideogram_house_mouse_chromosome_3.svg.png) | Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 A3 | Start | 32,871,695 bp[2] |
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End | 32,992,220 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Skeletal muscle tissue of biceps brachii
- glutes
- thoracic diaphragm
- deltoid muscle
- vastus lateralis muscle
- tibialis anterior muscle
- triceps brachii muscle
- Skeletal muscle tissue of rectus abdominis
- right ventricle
- myocardium of left ventricle
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| Top expressed in | - interventricular septum
- muscle of thigh
- triceps brachii muscle
- temporal muscle
- sternocleidomastoid muscle
- digastric muscle
- soleus muscle
- myocardium of ventricle
- gastrocnemius muscle
- skeletal muscle tissue
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/a/a2/PBB_GE_USP13_205356_at_fs.png/250px-PBB_GE_USP13_205356_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - cysteine-type peptidase activity
- chaperone binding
- zinc ion binding
- BAT3 complex binding
- metal ion binding
- ubiquitin-like protein-specific protease activity
- proteasome binding
- peptidase activity
- ubiquitin binding
- protein binding
- ubiquitin-like protein ligase binding
- hydrolase activity
- ubiquitin protein ligase binding
- thiol-dependent deubiquitinase
- cysteine-type endopeptidase activity
| Cellular component | | Biological process | - regulation of transcription, DNA-templated
- ubiquitin-dependent protein catabolic process
- positive regulation of ERAD pathway
- proteolysis
- autophagy
- regulation of autophagy
- protein K63-linked deubiquitination
- maintenance of unfolded protein involved in ERAD pathway
- cell population proliferation
- melanocyte differentiation
- protein deubiquitination
- protein K29-linked deubiquitination
- protein K6-linked deubiquitination
- protein stabilization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 3: 179.65 – 179.8 Mb | Chr 3: 32.87 – 32.99 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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