USP33 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Protein_USP33_PDB_2uzg.png/250px-Protein_USP33_PDB_2uzg.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | USP33, VDU1, ubiquitin specific peptidase 33 |
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External IDs | OMIM: 615146; MGI: 2159711; HomoloGene: 8996; GeneCards: USP33; OMA:USP33 - orthologs |
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Gene location (Human) |
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![Chromosome 1 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png) | Chr. | Chromosome 1 (human)[1] |
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| Band | 1p31.1 | Start | 77,695,987 bp[1] |
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End | 77,759,852 bp[1] |
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Gene location (Mouse) |
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![Chromosome 3 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Ideogram_house_mouse_chromosome_3.svg/260px-Ideogram_house_mouse_chromosome_3.svg.png) | Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 H3 | Start | 152,052,115 bp[2] |
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End | 152,099,254 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - cerebellar vermis
- Brodmann area 23
- retinal pigment epithelium
- pons
- lateral nuclear group of thalamus
- mucosa of paranasal sinus
- parietal pleura
- primary visual cortex
- endothelial cell
- middle temporal gyrus
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| Top expressed in | - neural layer of retina
- ventromedial nucleus
- lobe of cerebellum
- ventral tegmental area
- mammillary body
- dorsomedial hypothalamic nucleus
- pontine nuclei
- habenula
- lateral hypothalamus
- dorsal tegmental nucleus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/1/10/PBB_GE_USP33_214843_s_at_fs.png/250px-PBB_GE_USP33_214843_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/9/97/PBB_GE_USP33_212513_s_at_fs.png/250px-PBB_GE_USP33_212513_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - cysteine-type peptidase activity
- zinc ion binding
- metal ion binding
- peptidase activity
- ubiquitin binding
- protein binding
- thiol-dependent deubiquitinase
- cysteine-type endopeptidase activity
- hydrolase activity
- G protein-coupled receptor binding
| Cellular component | - cytoplasm
- cell body
- centrosome
- Golgi apparatus
- VCB complex
- focal adhesion
- nucleoplasm
- microtubule organizing center
- autophagosome
- perinuclear region of cytoplasm
- cytoskeleton
- cytosol
| Biological process | - endocytosis
- protein K48-linked deubiquitination
- ubiquitin-dependent protein catabolic process
- regulation of G protein-coupled receptor signaling pathway
- centrosome duplication
- cellular response to starvation
- protein stabilization
- negative regulation of protein binding
- proteolysis
- axon guidance
- regulation of autophagy
- protein K63-linked deubiquitination
- positive regulation of protein binding
- cell migration
- protein deubiquitination
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_015017 NM_201624 NM_201626 |
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NM_001076676 NM_001252486 NM_133247 NM_001355666 |
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RefSeq (protein) | NP_055832 NP_963918 NP_963920 NP_001364359 NP_001364360
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NP_001364361 NP_001364362 NP_001364363 NP_001364364 NP_001364365 NP_001364366 NP_001364367 NP_001364368 |
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NP_001070144 NP_001239415 NP_573510 NP_001342595 |
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Location (UCSC) | Chr 1: 77.7 – 77.76 Mb | Chr 3: 152.05 – 152.1 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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