YLPM1

Protein-coding gene in the species Homo sapiens
YLPM1
Identifiers
AliasesYLPM1, C14orf170, PPP1R169, ZAP113, ZAP3, YLP motif containing 1
External IDsMGI: 1926195; HomoloGene: 87707; GeneCards: YLPM1; OMA:YLPM1 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for YLPM1
Genomic location for YLPM1
Band14q24.3Start74,763,316 bp[1]
End74,859,435 bp[1]
Gene location (Mouse)
Chromosome 12 (mouse)
Chr.Chromosome 12 (mouse)[2]
Chromosome 12 (mouse)
Genomic location for YLPM1
Genomic location for YLPM1
Band12|12 D1Start85,043,095 bp[2]
End85,117,289 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • ganglionic eminence

  • tendon of biceps brachii

  • sural nerve

  • sperm

  • ventricular zone

  • right uterine tube

  • left ovary

  • right ovary

  • internal globus pallidus

  • right hemisphere of cerebellum
Top expressed in
  • saccule

  • otic placode

  • otic vesicle

  • tail of embryo

  • Paneth cell

  • ureter

  • genital tubercle

  • motor neuron

  • ventricular zone

  • renal corpuscle
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • RNA binding
  • DNA-binding transcription repressor activity, RNA polymerase II-specific
Cellular component
  • nucleus
  • nucleoplasm
  • cytosol
  • nuclear speck
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • negative regulation of transcription by RNA polymerase II
  • biological process
  • regulation of telomere maintenance
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

56252

56531

Ensembl

ENSG00000119596

ENSMUSG00000021244

UniProt

P49750

Q9R0I7

RefSeq (mRNA)

NM_019589

NM_178363
NM_001347421

RefSeq (protein)

NP_062535

NP_001334350
NP_848140

Location (UCSC)Chr 14: 74.76 – 74.86 MbChr 12: 85.04 – 85.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

YLP motif-containing protein 1 is a protein that in humans is encoded by the YLPM1 gene.[5][6]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119596 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021244 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, et al. (Aug 1995). "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease". Nature. 375 (6534): 754–60. Bibcode:1995Natur.375..754S. doi:10.1038/375754a0. PMID 7596406. S2CID 4308372.
  6. ^ "Entrez Gene: YLPM1 YLP motif containing 1".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. Bibcode:2003Natur.421..601H. doi:10.1038/nature01348. PMID 12508121.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Armstrong L, Lako M, van Herpe I, et al. (2005). "A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation". Mech. Dev. 121 (12): 1509–22. doi:10.1016/j.mod.2004.07.005. PMID 15511642.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Ulke-Lemée A, Trinkle-Mulcahy L, Chaulk S, et al. (2007). "The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G". Biochim. Biophys. Acta. 1774 (10): 1339–50. doi:10.1016/j.bbapap.2007.07.015. PMID 17890166.
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