Arsenit-transportujuća ATPaza
| Arsenit-transportujuća ATPaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.3.16 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Arsenit-transportujuća ATPaza (EC 3.6.3.16, Arsenite-transporting ATPase) je enzim sa sistematskim imenom ATP fosfohidrolaza (eksport arsenita).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + H2O + arsenitein ADP + fosfat + arseniteout
Ova multipodjednična nefosforilisana ATPaza učestvuje u transportu jona.
Reference
- ↑ Silver, S., Misra, T.K. and Laddaga, R.A. (1989). „DNA sequence analysis of bacterial toxic heavy metal resistance”. Biol. Trace Elem. Res. 21: 145-163. PMID 2484581.
- ↑ Rosen, B.P., Weigel, U., Monticello, R.A. and Edwards, B.P. (1991). „Molecular analysis of an anion pump: purification of the ArsC protein”. Arch. Biochem. Biophys. 284: 381-385. PMID 1703401.
- ↑ Bruhn, D.F., Li, J., Silver, S., Roberto, F. and Rosen, B.P. (1996). „The arsenical resistance operon of IncN plasmid R46”. FEMS Microbiol. Lett. 139: 149-153. PMID 8674982.
- ↑ Zhou, T., Rosen, B.P. and Gatti, D.L. (1999). „Crystallization and preliminary X-ray analysis of the catalytic subunit of the ATP-dependent arsenite pump encoded by the Escherichia coli plasmid R773”. Acta Crystallogr. D Biol. Crystallogr. 55: 921-924. PMID 10089335.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH Arsenite-transporting+ATPase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
