Diacilglicerol kinaza
Diacilglicerol kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.107 | ||||||||
CAS broj | 60382-71-0 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Diacilglicerol kinaza (EC 2.7.1.107, digliceridna kinaza, 1,2-diacilglicerolna kinaza (fosforilacija), 1,2-diacilglicerolna kinaza, sn-1,2-diacilglicerolna kinaza, DG kinaza, DGK, ATP:diacilglicerol fosfotransferaza, arahidonoil-specifična diacilglicerolna kinaza, diacilglicerol:ATP kinaza, ATP:1,2-diacilglicerol 3-fosfotransferaza) je enzim sa sistematskim imenom ATP:1,2-diacil-sn-glicerol 3-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + 1,2-diacil-sn-glicerol ADP + 1,2-diacil-sn-glicerol 3-fosfat
Reference
- ↑ Daleo, G.R., Piras, M.M. and Piras, R. (1976). „Diglyceride kinase activity of microtubules. Characterization and comparison with the protein kinase and ATPase activities associated with vinblastine-isolated tubulin of chick embryonic muscles”. Eur. J. Biochem. 68: 339-346. PMID 185051.
- ↑ Hokin, L.E. and Hokin, M.R. (1963). „Diglyceride kinase and other pathways for phosphatidic acid synthesis in the erythrocyte membrane”. Biochim. Biophys. Acta 67: 470-484. PMID 13961253.
- ↑ Weissbach, H., Thomas, E. and Kaback, H.R. (1971). „Studies on the metabolism of ATP by isolated bacterial membranes: formation and metabolism of membrane-bound phosphatidic acid”. Arch. Biochem. Biophys. 147: 249-254. PMID 4940043.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Diacylglycerol+kinase+(ATP+dependent)
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6