L-ksiluloza reduktaza
L-ksiluloza reduktaza | |||||||||
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L-ksiluloza reduktaza tetramer, Human | |||||||||
Identifikatori | |||||||||
EC broj | 1.1.1.10 | ||||||||
CAS broj | 9028-17-5 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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L-ksiluloza reduktaza (EC 1.1.1.10, L-ksilulozna reduktaza, ksilitol dehidrogenaza) je enzim sa sistematskim imenom ksilitol:NADP+ 4-oksidoreduktaza (formira L-ksilulozu).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ksilitol + NADP+ L-ksiluloza + NADPH + H+
Reference
- ↑ Doten, R.C. and Mortlock, R.P. (1985). „Characterization of xylitol-utilizing mutants of Erwinia uredovora”. J. Bacteriol. 161: 529-533. PMID 2981816.
- ↑ Hickman, J. and Ashwell, G. (1959). „A sensitive and stereospecific enzymatic assay for xylulose”. J. Biol. Chem. 234: 758-761. PMID 13654257.
- ↑ Hollmann, S. and Touster, O. (1957). „The L-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria”. J. Biol. Chem. 225: 87-102. PMID 13416220.
- ↑ Touster, O., Reynolds, V.H. and Hutcheson, R.M. (1956). „The reduction of L-xylulose to xylitol by guinea pig liver mitochondria”. J. Biol. Chem. 221: 697-709. PMID 13357463.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH L-xylulose+reductase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6