CTP sintaza

CTP sintaza
CTP sintetaza tetramer, Human
Identifikatori
EC broj6.3.4.2
CAS broj9023-56-7
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

CTP sintaza (EC 6.3.4.2, UTP—amonijak ligaza, citidin trifosfatna sintetaza, uridin trifosfatna aminaza, citidin 5'-trifosfatna sintetaza) je enzim sa sistematskim imenom UTP:amonijak ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + UTP + NH3 {\displaystyle \rightleftharpoons } ADP + fosfat + CTP

Glutamin može da zameni NH3.

Reference

  1. ^ Lieberman, I. (1956). „Enzymatic amination of uridine triphosphate to cytidine triphosphate”. J. Biol. Chem. 222: 765—775. PMID 13367044. 
  2. ^ Long, C.W., Levitzki, A., Houston, L.L and Koshland, D.E., Jr. (1969). „Subunit structures and interactions of CTP synthetase”. Fed. Proc. 28: 342—342. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
  • William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

  • CTP+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
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Enzimi: CO CS i CN ligaza (EC 6.1-6.3)
6.1: Ugljenik-kiseonik6.2: Ugljenik-sumpor6.3: Ugljenik-azot
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