Timidin kinaza
Timidin kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.21 | ||||||||
CAS broj | 2594110 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Timidin kinaza (EC 2.7.1.21, timidinska kinaza (fosforilacija), 2'-dezoksitimidinska kinaza, dezoksitimidinska kinaza (fosforilacija)) je enzim sa sistematskim imenom ATP:timidin 5'-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Dezoksiuridin takođe može da deluje kao akceptor. dGTP može da deluje kao donor.
Reference
- ^ Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. (1982). „Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase”. Biochim. Biophys. Acta. 708: 99—103. PMID 6293576. CS1 одржавање: Вишеструка имена: списак аутора (веза)
- ^ Kizer, D.E. & Holman, L. (1974). „Purification and properties of thymidine kinase from regenerating rat liver”. Biochim. Biophys. Acta. 350: 193—200. PMID 4407348.
- ^ Okazaki, R. & Kornberg, A. (1964). „Deoxythymidine kinase of Escherichia coli. I. Purification and some properties of the enzyme”. J. Biol. Chem. 239: 269—274. PMID 14114853.
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- Thymidine+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- EC1 Oksidoreduktaze /spisak
- EC2 Transferaze /spisak
- EC3 Hidrolaze /spisak
- EC4 Lijaze /spisak
- EC5 Izomeraze /spisak
- EC6 Ligaze /spisak
- B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6