6-硝基喹哌嗪
- 未分配
- Uncontrolled
- 6-nitro-2-piperazin-1-yl-quinoline
![☒](http://upload.wikimedia.org/wikipedia/commons/thumb/a/a2/X_mark.svg/7px-X_mark.svg.png)
- 5012
- 4837
Y
- 28M0X094BH
- ChEMBL41140
Y
- DTXSID7044001
- 交互式图像
- [O-][N+](=O)c3cc1c(nc(cc1)N2CCNCC2)cc3
- InChI=1S/C13H14N4O2/c18-17(19)11-2-3-12-10(9-11)1-4-13(15-12)16-7-5-14-6-8-16/h1-4,9,14H,5-8H2
Y
- Key:GGDBEAVVGFNWIA-UHFFFAOYSA-N
Y
6-硝基喹哌嗪(英語:6-Nitroquipazine,开发代号:DU-24565)是一种含氮有机化合物,化学式为C13H14N4O2,是一种喹哌嗪衍生物,能作为选择性的5-羟色胺再摄取抑制剂,用于科学研究[1][2],可在体外(in-vitro)抑制黑素細胞生成[3]。
参考文献
- ^ Vaatstra WJ, Deiman-Van Aalst WM, Eigeman L. Du 24565, a quipazine derivative, a potent selective serotonin uptake inhibitor. European Journal of Pharmacology. March 1981, 70 (2): 195–202. PMID 6973481. doi:10.1016/0014-2999(81)90214-4.
- ^ Classen K, Göthert M, Schlicker E. Effects of DU 24565 (6-nitroquipazine) on serotoninergic and noradrenergic neurones of the rat brain and comparison with the effects of quipazine. Naunyn-Schmiedeberg's Archives of Pharmacology. June 1984, 326 (3): 198–202. PMID 6206407. S2CID 20858707. doi:10.1007/bf00505318.
- ^ McEwan M, Parsons PG. Inhibition of melanization in human melanoma cells by a serotonin uptake inhibitor. The Journal of Investigative Dermatology. July 1987, 89 (1): 82–86. PMID 3110297. doi:10.1111/1523-1747.ep12580425. No-cost access but non-free license.