16α-氰基孕酮
16α-氰基孕酮 | |
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IUPAC名 3β-Hydroxy-20-oxopregn-5-ene-16α-carbonitrile | |
系统名 (1S,2R,3as,3bS,7S,9aR,9bS,11aS)-1-Acetyl-7-hydroxy-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthrene-2-carbonitrile | |
识别 | |
CAS号 | 1434-54-4 ![]() |
PubChem | 15032 |
ChemSpider | 14308 |
SMILES |
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InChI |
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InChIKey | VSBHRRMYCDQLJF-ZDNYCOCVBP |
IUPHAR配体 | 2762 |
性质 | |
化学式 | C22H31NO2 |
摩尔质量 | 341.49 g/mol g·mol⁻¹ |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
16α-氰基孕酮(英語:Pregnenolone 16α-carbonitrile,缩写为PCN)是一种含氮有机化合物,分子式C22H31NO2,是一种人工合成的甾体类抗糖皮质激素(英语:Antiglucocorticoid),也是孕甾烷X受体(英语:Pregnane X receptor)的激动剂。[1][2][3]
参考文献
- ^ J.I. Mason. Genetics of Steroid Biosynthesis and Function. CRC Press. 2 September 2003: 449–. ISBN 978-0-203-30149-4.
- ^ Giacinto Bagetta; Marco Cosentino; Marie Tiziana Corasaniti; Shinobu Sakurada. Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health. CRC Press. 19 April 2016: 250–. ISBN 978-1-4398-3769-6.
- ^ Larisa Y. Poluektova; J. Victor Garcia-Martinez; Yoshio Koyanagi; Markus G. Manz; Andrew M. Tager. Humanized Mice for HIV Research. Springer. 18 February 2015: 350–. ISBN 978-1-4939-1655-9.