ADRB2 |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 4QKX, 2R4R, 2R4S, 2RH1, 3D4S, 3KJ6, 3NY8, 3NY9, 3NYA, 3P0G, 3PDS, 3SN6, 4GBR, 4LDE, 4LDL, 4LDO, 5D5A, 5D5B, 5JQH | | |
Ідентифікатори |
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Символи | ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR, adrenoceptor beta 2 |
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Зовнішні ІД | OMIM: 109690 MGI: 87938 HomoloGene: 30948 GeneCards: ADRB2 |
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Реагує на сполуку |
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arformoterol, фенотерол, формотерол, Індакатерол, mirabegron, olodaterol, орципреналін, vilanterol, zinterol, адреналін, ізопреналін, сальметерол, Добутамін, Ефедрин, піндолол, сальбутамол, тербуталін, alprenolol, атенолол, бетаксолол, bupranolol, carazolol, карведилол, cicloprolol, лабеталол, levobetaxolol, levobunolol, метопролол, надолол, пропафенон, пропранолол, соталол, sr-59230a free base, Ізоксуприн, pirbuterol, reproterol, адреналін, vilanterol, норадреналін, Ефедрин, кленбутерол, carmoterol, PF-610355, isoproterenol hydrochloride, procaterol, bitolterol mesylate, carteolol hydrochloride, dipivefrin hydrochloride, DL-dobutamine hydrochloride, esmolol hydrochloride, levobunolol hydrochloride, propafenone hydrochloride, propranolol hydrochloride, sotalol hydrochloride, timolol maleate[1] |
Онтологія гена |
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Молекулярна функція | • adenylate cyclase binding • adrenergic receptor activity • beta2-adrenergic receptor activity • enzyme binding • protein homodimerization activity • potassium channel regulator activity • GO:0001948, GO:0016582 protein binding • G protein-coupled receptor activity • signal transducer activity • norepinephrine binding • epinephrine binding • amyloid-beta binding • GO:0032403 protein-containing complex binding |
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Клітинна компонента | • ендосома • мембрана • клітинне ядро • apical plasma membrane • лізосома • integral component of membrane • receptor complex • клітинна мембрана • early endosome • integral component of plasma membrane • endosome membrane • clathrin-coated vesicle membrane |
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Біологічний процес | • positive regulation of autophagosome maturation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • regulation of sodium ion transport • endosome to lysosome transport • рецептор-опосередкований ендоцитоз • cell surface receptor signaling pathway • regulation of systemic arterial blood pressure by norepinephrine-epinephrine • negative regulation of smooth muscle contraction • regulation of smooth muscle contraction • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • кісткова резорбція • adenylate cyclase-activating adrenergic receptor signaling pathway • heat generation • desensitization of G protein-coupled receptor signaling pathway by arrestin • positive regulation of MAPK cascade • G protein-coupled receptor signaling pathway • positive regulation of bone mineralization • activation of adenylate cyclase activity • brown fat cell differentiation • activation of transmembrane receptor protein tyrosine kinase activity • positive regulation of protein ubiquitination • negative regulation of multicellular organism growth • cell-cell signaling • diet induced thermogenesis • norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure • positive regulation of lipophagy • response to cold • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0072468 сигнальна трансдукція • protein deubiquitination • membrane organization • adrenergic receptor signaling pathway • дія на кровоносні судини • positive regulation of protein kinase A signaling • positive regulation of mini excitatory postsynaptic potential • positive regulation of protein serine/threonine kinase activity • positive regulation of cold-induced thermogenesis • cellular response to amyloid-beta • response to psychosocial stress • positive regulation of cAMP-dependent protein kinase activity • positive regulation of AMPA receptor activity |
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Джерела:Amigo / QuickGO | |
Шаблон експресії |
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Більше даних |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | |
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RefSeq (білок) | | |
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Локус (UCSC) | Хр. 5: 148.83 – 148.83 Mb | Хр. 18: 62.31 – 62.31 Mb |
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PubMed search | [2] | [3] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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