BRSK2 |
---|
|
Identifiers |
---|
Aliases | BRSK2, C11orf7, PEN11B, SAD1, SADA, STK29, BR serine/threonine kinase 2, SAD-A |
---|
External IDs | OMIM: 609236; MGI: 1923020; HomoloGene: 123829; GeneCards: BRSK2; OMA:BRSK2 - orthologs |
---|
EC number | 2.7.11.26 |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 11 (human)[1] |
---|
| Band | 11p15.5 | Start | 1,389,899 bp[1] |
---|
End | 1,462,689 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 7 (mouse)[2] |
---|
| Band | 7|7 F5 | Start | 141,503,488 bp[2] |
---|
End | 141,557,984 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - right hemisphere of cerebellum
- body of pancreas
- right frontal lobe
- ganglionic eminence
- anterior cingulate cortex
- Brodmann area 9
- prefrontal cortex
- C1 segment
- nucleus accumbens
- amygdala
|
| Top expressed in | - visual cortex
- primary visual cortex
- superior frontal gyrus
- dentate gyrus of hippocampal formation granule cell
- neural layer of retina
- cerebellar cortex
- prefrontal cortex
- hippocampus proper
- ganglionic eminence
- lumbar subsegment of spinal cord
|
| More reference expression data |
|
---|
BioGPS | | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - transferase activity
- nucleotide binding
- protein kinase activity
- ATPase binding
- ATPase regulator activity
- metal ion binding
- kinase activity
- protein kinase binding
- magnesium ion binding
- tau-protein kinase activity
- protein serine/threonine kinase activity
- ATP binding
- tau protein binding
| Cellular component | - centrosome
- microtubule organizing center
- perinuclear region of cytoplasm
- cytoskeleton
- nucleus
- cytoplasm
- endoplasmic reticulum
- distal axon
| Biological process | - actin cytoskeleton reorganization
- neuron projection morphogenesis
- ERAD pathway
- phosphorylation
- nervous system development
- cell division
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
- G2/M transition of mitotic cell cycle
- peptidyl-serine phosphorylation
- cell cycle
- regulation of ATP-dependent activity
- regulation of retrograde protein transport, ER to cytosol
- exocytosis
- apoptotic process
- establishment of cell polarity
- regulation of insulin secretion involved in cellular response to glucose stimulus
- axonogenesis
- protein phosphorylation
- neuron differentiation
- regulation of neuron projection development
- intracellular signal transduction
- regulation of axonogenesis
- microtubule cytoskeleton organization involved in establishment of planar polarity
- regulation of synaptic vesicle clustering
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | |
---|
NM_001256627 NM_001256629 NM_001256630 NM_001282218 NM_003957 |
| |
---|
NM_001009929 NM_001009930 NM_001276763 NM_029426 |
|
---|
RefSeq (protein) | |
---|
NP_001243556 NP_001243558 NP_001243559 NP_001269147 NP_003948 |
| |
---|
NP_001009929 NP_001009930 NP_001263692 NP_083702 |
|
---|
Location (UCSC) | Chr 11: 1.39 – 1.46 Mb | Chr 7: 141.5 – 141.56 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|