MAP3K9 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3DTC, 4UY9 |
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Identifiers |
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Aliases | MAP3K9, MEKK9, MLK1, PRKE1, mitogen-activated protein kinase kinase kinase 9 |
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External IDs | OMIM: 600136; MGI: 2449952; HomoloGene: 76377; GeneCards: MAP3K9; OMA:MAP3K9 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 14 (human)[1] |
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| Band | 14q24.2 | Start | 70,722,526 bp[1] |
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End | 70,809,534 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 12 (mouse)[2] |
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| Band | 12|12 D1 | Start | 81,767,784 bp[2] |
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End | 81,827,949 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - buccal mucosa cell
- lateral nuclear group of thalamus
- cerebellar vermis
- Pars compacta
- frontal pole
- postcentral gyrus
- amniotic fluid
- pars reticulata
- orbitofrontal cortex
- middle temporal gyrus
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| Top expressed in | - granulocyte
- primary visual cortex
- superior frontal gyrus
- lip
- dentate gyrus of hippocampal formation granule cell
- esophagus
- zygote
- cerebellar cortex
- neural layer of retina
- ventricular zone
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- nucleotide binding
- protein kinase activity
- protein homodimerization activity
- kinase activity
- protein serine/threonine kinase activity
- protein binding
- ATP binding
- MAP kinase kinase kinase activity
- MAP kinase kinase activity
- JUN kinase kinase kinase activity
| Cellular component | - cytoplasm
- cellular component
- intracellular anatomical structure
| Biological process | - regulation of transcription, DNA-templated
- phosphorylation
- cell death
- transcription, DNA-templated
- protein phosphorylation
- positive regulation of apoptotic process
- protein autophosphorylation
- apoptotic process
- MAPK cascade
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001284230 NM_001284231 NM_001284232 NM_033141 |
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RefSeq (protein) | |
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NP_001271159 NP_001271160 NP_001271161 NP_149132 |
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Location (UCSC) | Chr 14: 70.72 – 70.81 Mb | Chr 12: 81.77 – 81.83 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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