KRT24

Protein-coding gene in the species Homo sapiens
KRT24
Identifiers
AliasesKRT24, K24, KA24, keratin 24
External IDsOMIM: 607742; MGI: 1922956; HomoloGene: 10379; GeneCards: KRT24; OMA:KRT24 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT24
Genomic location for KRT24
Band17q21.2Start40,697,991 bp[1]
End40,703,752 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for KRT24
Genomic location for KRT24
Band11|11 DStart99,170,785 bp[2]
End99,176,088 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • amniotic fluid

  • gonad

  • tail of epididymis

  • mucosa of pharynx

  • buccal mucosa cell

  • corpus epididymis

  • mucosa of esophagus

  • periodontal fiber

  • nasal epithelium

  • testicle
Top expressed in
  • skin of external ear

  • lip

  • interventricular septum

  • molar

  • skin of back

  • soleus muscle

  • knee joint

  • triceps brachii muscle

  • ciliary body

  • endothelial cell of lymphatic vessel
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • structural molecule activity
  • molecular function
Cellular component
  • extracellular exosome
  • intermediate filament
  • cytosol
Biological process
  • keratinization
  • cornification
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

192666

75706

Ensembl

ENSG00000167916

ENSMUSG00000020913

UniProt

Q2M2I5

A1L317

RefSeq (mRNA)

NM_019016

NM_029393

RefSeq (protein)

NP_061889

NP_083669

Location (UCSC)Chr 17: 40.7 – 40.7 MbChr 11: 99.17 – 99.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

KRT24 is a keratin gene that also influences cellular responses to apoptotic signals. It produces a cytokeratin-like protein of 525 amino acids.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167916 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020913 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sprecher E, Itin P, Whittock NV, McGrath JA, Meyer R, DiGiovanna JJ, et al. (September 2002). "Refined mapping of Naegeli-Franceschetti- Jadassohn syndrome to a 6 cM interval on chromosome 17q11.2-q21 and investigation of candidate genes". The Journal of Investigative Dermatology. 119 (3): 692–698. doi:10.1046/j.1523-1747.2002.01855.x. PMID 12230514.
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Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman
See also: cytoskeletal defects
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