KRT38

Protein-coding gene in the species Homo sapiens
KRT38
Identifiers
AliasesKRT38, HA8, KRTHA8, hHa8, keratin 38
External IDsOMIM: 604542; HomoloGene: 68361; GeneCards: KRT38; OMA:KRT38 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT38
Genomic location for KRT38
Band17q21.2Start41,436,154 bp[1]
End41,440,983 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • hair follicle

  • skin of thigh

  • skin of abdomen

  • pharynx

  • tonsil

  • head

  • gonad

  • mouth

  • mucosa of esophagus

  • salivary gland
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • structural molecule activity
Cellular component
  • intermediate filament
  • extracellular exosome
  • cytosol
Biological process
  • keratinization
  • cornification
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8687

n/a

Ensembl

ENSG00000171360

n/a

UniProt

O76015

n/a

RefSeq (mRNA)

NM_006771

n/a

RefSeq (protein)

NP_006762

n/a

Location (UCSC)Chr 17: 41.44 – 41.44 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

KRT38 is a keratin gene. Its corresponding protein is asymmetrically distributed within human hair follicles.[3] It does not have murine[4] or equine[5] orthologs. The encoded protein is a type I keratin and a hair keratin.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171360 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Westgate GE, Ginger RS, Green MR (June 2017). "The biology and genetics of curly hair". Experimental Dermatology. 26 (6): 483–490. doi:10.1111/exd.13347. hdl:10454/14702. PMID 28370528. S2CID 44671559.
  4. ^ Takan I, Karakülah G, Louka A, Pavlopoulou A (17 March 2023). ""In the light of evolution:" keratins as exceptional tumor biomarkers". PeerJ. 11: e15099. doi:10.7717/peerj.15099. PMC 10026720. PMID 36949761.
  5. ^ Balmer P, Bauer A, Pujar S, McGarvey KM, Welle M, Galichet A, et al. (28 August 2017). "A curated catalog of canine and equine keratin genes". PLOS ONE. 12 (8): e0180359. Bibcode:2017PLoSO..1280359B. doi:10.1371/journal.pone.0180359. PMC 5573215. PMID 28846680.
  • v
  • t
  • e
  • v
  • t
  • e
Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman
See also: cytoskeletal defects