KRT27

Protein-coding gene in the species Homo sapiens
KRT27
Identifiers
AliasesKRT27, KRT25C, K25IRS3, keratin 27
External IDsOMIM: 616676; MGI: 1339999; HomoloGene: 7805; GeneCards: KRT27; OMA:KRT27 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT27
Genomic location for KRT27
Band17q21.2Start40,776,808 bp[1]
End40,782,550 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for KRT27
Genomic location for KRT27
Band11 D|11 62.92 cMStart99,236,391 bp[2]
End99,241,930 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of arm

  • testicle

  • skin of hip

  • skin of leg

  • skin of abdomen

  • nipple

  • right lung

  • right coronary artery

  • mucosa of transverse colon

  • gallbladder
Top expressed in
  • hair follicle

  • lip

  • lumbar spinal ganglion

  • skin of back

  • skin of abdomen

  • embryo

  • lower jaw

  • Meckel's cartilage

  • skin of external ear

  • sexually immature organism
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • structural molecule activity
  • molecular function
Cellular component
  • cytoplasm
  • extracellular exosome
  • intermediate filament
  • cytosol
Biological process
  • hair follicle morphogenesis
  • keratinization
  • cornification
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

342574

16675

Ensembl

ENSG00000171446

ENSMUSG00000017588

UniProt

Q7Z3Y8

Q9Z320

RefSeq (mRNA)

NM_181537

NM_010666

RefSeq (protein)

NP_853515

NP_034796

Location (UCSC)Chr 17: 40.78 – 40.78 MbChr 11: 99.24 – 99.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Keratin, type I cytoskeletal 27 is a keratin belonging to the Type I family of intermediate filament proteins.[5] In humans, in it encoded by a gene with symbol KRT27.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171446 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017588 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "KRT27 keratin 27 - NIH Genetic Testing Registry (GTR) - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-06-25.
  • v
  • t
  • e
  • v
  • t
  • e
Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman
See also: cytoskeletal defects