KRT25

Protein-coding gene in the species Homo sapiens
KRT25
Identifiers
AliasesKRT25, KRT25A, ARWH3, KRT24IRS1, keratin 25
External IDsOMIM: 616646; MGI: 1918060; HomoloGene: 77127; GeneCards: KRT25; OMA:KRT25 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT25
Genomic location for KRT25
Band17q21.2Start40,748,021 bp[1]
End40,755,331 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for KRT25
Genomic location for KRT25
Band11|11 DStart99,206,342 bp[2]
End99,213,777 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of arm

  • skin of hip

  • testicle

  • sperm

  • nipple

  • gonad

  • tibialis anterior muscle

  • skin of thigh

  • deltoid muscle

  • skin of abdomen
Top expressed in
  • hair follicle

  • lip

  • skin of back

  • sexually immature organism

  • skin of external ear

  • skin of abdomen

  • primary oocyte

  • secondary oocyte

  • zygote

  • cerebellum
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • structural molecule activity
  • protein heterodimerization activity
  • molecular function
Cellular component
  • cytoplasm
  • extracellular exosome
  • intermediate filament
  • cytosol
Biological process
  • hair cycle
  • hair follicle morphogenesis
  • intermediate filament organization
  • human ageing
  • cytoskeleton organization
  • keratinization
  • cornification
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

147183

70810

Ensembl

ENSG00000204897

ENSMUSG00000035831

UniProt

Q7Z3Z0

Q8VCW2

RefSeq (mRNA)

NM_181534

NM_133730

RefSeq (protein)

NP_853512

NP_598491

Location (UCSC)Chr 17: 40.75 – 40.76 MbChr 11: 99.21 – 99.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

KRT25 (full name keratin 25) is a gene encoding for a protein in the type I keratin family.[5] The gene is encoded on a region of chromosome 17q21.2.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000204897 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035831 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "KRT25 keratin [Homo sapiens (human)]". NCBI. 14 October 2023. Retrieved 27 October 2023.
  6. ^ "Gene Symbol Report". HUGO Gene Nomenclature Committee. 27 October 2023. Retrieved 27 October 2023.
  • v
  • t
  • e
  • v
  • t
  • e
Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman
See also: cytoskeletal defects