OR10G2

Protein-coding gene in the species Homo sapiens
OR10G2
Identifiers
AliasesOR10G2, OR14-41, olfactory receptor family 10 subfamily G member 2
External IDsMGI: 3031345; HomoloGene: 87788; GeneCards: OR10G2; OMA:OR10G2 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for OR10G2
Genomic location for OR10G2
Band14q11.2Start21,633,836 bp[1]
End21,634,940 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for OR10G2
Genomic location for OR10G2
Band14|14 C2Start52,627,251 bp[2]
End52,634,836 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • lymph node

  • appendix

  • spleen
Top expressed in
  • blastocyst

  • hypothalamus

  • neural tube

  • olfactory bulb
More reference expression data
BioGPS


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26534

258268

Ensembl

ENSG00000255582

ENSMUSG00000063867

UniProt

n
a

E9PWU0

RefSeq (mRNA)

NM_001005466

NM_146271

RefSeq (protein)

n/a

NP_666383

Location (UCSC)Chr 14: 21.63 – 21.63 MbChr 14: 52.63 – 52.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 10G2 is a protein that in humans is encoded by the OR10G2 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.[citation needed] Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000255582 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063867 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Koop BF, Rowen L, Wang K, Kuo CL, Seto D, Lenstra JA, Howard S, Shan W, Deshpande P, Hood L (Jun 1994). "The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA". Genomics. 19 (3): 478–93. doi:10.1006/geno.1994.1097. PMID 8188290.
  6. ^ a b "Entrez Gene: OR10G2 olfactory receptor, family 10, subfamily G, member 2".

Further reading

  • Boysen C, Simon MI, Hood L (1997). "Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones". Genome Res. 7 (4): 330–8. doi:10.1101/gr.7.4.330. PMID 9110172.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


  • v
  • t
  • e
Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


Stub icon

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e