OR4C15

Protein-coding gene in the species Homo sapiens
OR4C15
Identifiers
AliasesOR4C15, OR11-127, OR11-134, olfactory receptor family 4 subfamily C member 15
External IDsMGI: 3031045; HomoloGene: 81548; GeneCards: OR4C15; OMA:OR4C15 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR4C15
Genomic location for OR4C15
Band11q11Start55,554,307 bp[1]
End55,555,419 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for OR4C15
Genomic location for OR4C15
Band2|2 E1Start88,757,220 bp[2]
End88,768,455 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gonad
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • transmembrane signaling receptor activity
  • signal transducer activity
  • olfactory receptor activity
  • G protein-coupled receptor activity
Cellular component
  • plasma membrane
  • membrane
  • integral component of membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • detection of chemical stimulus involved in sensory perception of smell
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

81309

258025

Ensembl

ENSG00000181939

ENSMUSG00000075112

UniProt

Q8NGM1

Q7TR09

RefSeq (mRNA)

NM_001001920

NM_001011804

RefSeq (protein)

NP_001001920

NP_001011804

Location (UCSC)Chr 11: 55.55 – 55.56 MbChr 2: 88.76 – 88.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4C15 is a protein that in humans is encoded by the OR4C15 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181939 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075112 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR4C15 olfactory receptor, family 4, subfamily C, member 15".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
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Family 13


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