OR5R1

Protein-coding gene in the species Homo sapiens
OR8U3
Identifiers
AliasesOR8U3, OR11-185, OR5R1P, olfactory receptor family 5 subfamily R member 1 (gene/pseudogene), olfactory receptor family 5 subfamily R member 1, OR5R1, olfactory receptor family 8 subfamily U member 3
External IDsMGI: 3030872; HomoloGene: 17463; GeneCards: OR8U3; OMA:OR8U3 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR8U3
Genomic location for OR8U3
Band11q12.1Start56,417,258 bp[1]
End56,418,232 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
    n/a
    n/a
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • odorant binding
  • olfactory receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception of smell
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

219479

259015

Ensembl

ENSG00000279961

ENSMUSG00000050577

UniProt

Q8NH85

Q8VGS1

RefSeq (mRNA)

NM_001004744

NM_147013

RefSeq (protein)

NP_001004744

NP_667224

Location (UCSC)Chr 11: 56.42 – 56.42 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 5R1 is a protein that in humans is encoded by the OR5R1 gene.[4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000279961 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ a b "Entrez Gene: OR5R1 olfactory receptor, family 5, subfamily R, member 1".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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(fish-like receptors)
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(tetrapod specific receptors)
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