OR10J3

Protein-coding gene in the species Homo sapiens
OR10J3
Identifiers
AliasesOR10J3, OR1-25, OR10J3P, olfactory receptor family 10 subfamily J member 3
External IDsMGI: 3030052; HomoloGene: 105155; GeneCards: OR10J3; OMA:OR10J3 - orthologs
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[1]
Chromosome 1 (mouse)
Genomic location for OR10J3
Genomic location for OR10J3
Band1|1 H3Start173,025,375 bp[1]
End173,033,903 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • prefrontal cortex

  • brain

  • esophagus

  • cerebral cortex

  • multicellular organism
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • transmembrane signaling receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • detection of chemical stimulus involved in sensory perception
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

441911

258880

Ensembl

n/a

ENSMUSG00000046643

UniProt

Q5JRS4

E9PWV2

RefSeq (mRNA)

NM_001004467

NM_001001809
NM_146880

RefSeq (protein)

NP_001004467

NP_001001809

Location (UCSC)n/aChr 1: 173.03 – 173.03 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 10J3 is a protein that in humans is encoded by the OR10J3 gene.[4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046643 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ a b "Entrez Gene: OR10J3 olfactory receptor, family 10, subfamily J, member 3".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


  • v
  • t
  • e
Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


Stub icon

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e