OR2B3

Protein-coding gene in the species Homo sapiens
OR2B3
Identifiers
AliasesOR2B3, 6M1-1, OR2B3P, OR6-14, OR6-4, olfactory receptor family 2 subfamily B member 3
External IDsHomoloGene: 67858; GeneCards: OR2B3; OMA:OR2B3 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for OR2B3
Genomic location for OR2B3
Band6p22.1Start29,086,208 bp[1]
End29,087,313 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • mucosa of transverse colon
    n/a
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception of smell
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

442184

n/a

Ensembl
ENSG00000233054
ENSG00000231319
ENSG00000206524
ENSG00000233687
ENSG00000226832

ENSG00000233180
ENSG00000225736
ENSG00000204703

n/a

UniProt

O76000

n/a

RefSeq (mRNA)

NM_001005226

n/a

RefSeq (protein)

NP_001005226

n/a

Location (UCSC)Chr 6: 29.09 – 29.09 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Putative olfactory receptor 2B3 is a protein that in humans is encoded by the OR2B3 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. ^ a b c ENSG00000231319, ENSG00000206524, ENSG00000233687, ENSG00000226832, ENSG00000233180, ENSG00000225736, ENSG00000204703 GRCh38: Ensembl release 89: ENSG00000233054, ENSG00000231319, ENSG00000206524, ENSG00000233687, ENSG00000226832, ENSG00000233180, ENSG00000225736, ENSG00000204703 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR2B3 olfactory receptor, family 2, subfamily B, member 3".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.135.3652. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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