OR4X1

Protein-coding gene in the species Homo sapiens
OR4X1
Identifiers
AliasesOR4X1, OR11-104, olfactory receptor family 4 subfamily X member 1 (gene/pseudogene), olfactory receptor family 4 subfamily X member 1
External IDsHomoloGene: 73447; GeneCards: OR4X1; OMA:OR4X1 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR4X1
Genomic location for OR4X1
Band11p11.2Start48,263,861 bp[1]
End48,264,778 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
    n/a
    n/a
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • transmembrane signaling receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • detection of chemical stimulus involved in sensory perception
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

390113

n/a

Ensembl

ENSG00000176567

n/a

UniProt

Q8NH49

n/a

RefSeq (mRNA)

NM_001004726

n/a

RefSeq (protein)

NP_001004726

n/a

Location (UCSC)Chr 11: 48.26 – 48.26 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 4X1 is a protein that in humans is encoded by the OR4X1 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single-coding exons. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.[citation needed] The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000176567 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR4X1 olfactory receptor, family 4, subfamily X, member 1".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
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Class II
(tetrapod specific receptors)
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