OR1D5

Protein-coding gene in humans
OR1D5
Identifiers
AliasesOR1D5, C17orf2, OR17-2, OR17-30, OR17-31, OR1D4, olfactory receptor family 1 subfamily D member 5
External IDsHomoloGene: 105312; GeneCards: OR1D5; OMA:OR1D5 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for OR1D5
Genomic location for OR1D5
Band17p13.3Start3,062,669 bp[1]
End3,063,607 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • signal transducer activity
  • G protein-coupled receptor activity
  • olfactory receptor activity
Cellular component
  • plasma membrane
  • membrane
  • integral component of membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
  • detection of chemical stimulus involved in sensory perception of smell
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8386

n/a

Ensembl

ENSG00000262628

n/a

UniProt

P58170

n/a

RefSeq (mRNA)

NM_014566

n/a

RefSeq (protein)

NP_055381

n/a

Location (UCSC)Chr 17: 3.06 – 3.06 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 1D5 is a protein that in humans is encoded by the OR1D5 gene.[3][4] [[ Olfactory receptors]] interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000262628 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. S2CID 23416814.
  4. ^ a b "Entrez Gene: OR1D5 olfactory receptor, family 1, subfamily D, member 5".

Further reading

  • Selbie LA, Townsend-Nicholson A, Iismaa TP, Shine J (1992). "Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences". Brain Res. Mol. Brain Res. 13 (1–2): 159–63. doi:10.1016/0169-328X(92)90057-I. PMID 1315913.
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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