OR11L1

Protein-coding gene in the species Homo sapiens
OR11L1
Identifiers
AliasesOR11L1, olfactory receptor family 11 subfamily L member 1
External IDsMGI: 3030157; HomoloGene: 64865; GeneCards: OR11L1; OMA:OR11L1 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for OR11L1
Genomic location for OR11L1
Band1q44Start247,840,928 bp[1]
End247,841,896 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for OR11L1
Genomic location for OR11L1
Band11|11 B1.3Start58,514,985 bp[2]
End58,521,327 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lobe of thyroid gland

  • left lobe of thyroid gland
Top expressed in
  • spermatid

  • stomach

  • segment of brain

  • prosencephalon
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • odorant binding
  • olfactory receptor activity
  • signal transducer activity
  • molecular function
Cellular component
  • integral component of membrane
  • plasma membrane
  • extracellular exosome
  • membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception of smell
  • G protein-coupled receptor signaling pathway
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

391189

258373

Ensembl

ENSG00000197591

ENSMUSG00000043880

UniProt

Q8NGX0

n/a

RefSeq (mRNA)

NM_001001959

NM_146376

RefSeq (protein)

NP_001001959

n/a

Location (UCSC)Chr 1: 247.84 – 247.84 MbChr 11: 58.51 – 58.52 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 11L1 is a protein that in humans is encoded by the OR11L1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197591 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043880 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR11L1 olfactory receptor, family 11, subfamily L, member 1".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
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Family 56
Class II
(tetrapod specific receptors)
Family 1
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